SCHEMBL5145010

SCHEMBL5145010

CN(CCO)c1cccc(O)c1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
TSHR P16473 1/20 0.59
CYP3A4 P08684 2/20 0.53
HTR7 P34969 12/20 0.51
MTNR1A P48039 2/20 0.44
MTNR1B P49286 2/20 0.44
CHRNB2 P17787 1/20 0.42
CHRNA4 P43681 1/20 0.42
MAP4K4 O95819 1/20 0.42
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
CA12 O43570 1/20 0.41
CA2 P00918 1/20 0.41
LMNA P02545 1/20 0.41
CA5A P35218 1/20 0.41
CA9 Q16790 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29591101 0.85 ALDH1A1 (0.59) ALDH1A1TSHRCYP3A4HTR7MTNR1A
SCHEMBL8403505 0.85 ALDH1A1 (0.59) ALDH1A1TSHRCYP3A4HTR7MTNR1A
SCHEMBL2388543 0.85 ALDH1A1 (0.59) ALDH1A1TSHRCYP3A4HTR7MTNR1A
SCHEMBL22166480 0.84 ALDH1A1 (0.63) ALDH1A1TSHRCYP3A4HTR7CHRNB2
SCHEMBL4500081 0.83 ALDH1A1 (0.57) ALDH1A1TSHRCYP3A4HTR7MTNR1A
SCHEMBL29235215 0.83 ALDH1A1 (0.57) ALDH1A1TSHRCYP3A4HTR7MTNR1A
SCHEMBL14818792 0.81 ALDH1A1 (0.55) ALDH1A1TSHRCYP3A4HTR7MTNR1A
SCHEMBL8095675 0.81 HTR7 (0.47) ALDH1A1CYP3A4HTR7MTNR1AMTNR1B
SCHEMBL9543205 0.80 ALDH1A1 (0.53) ALDH1A1TSHRCYP3A4HTR7MTNR1A
SCHEMBL4349572 0.80 ALDH1A1 (0.68) ALDH1A1TSHRCYP3A4HTR7CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1557157-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2007-03-07 EP claimed
US-7056353-B2 Composition for the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-06-06 US claimed
EP-1428503-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2006-05-10 EP claimed
US-6991660-B2 Composition for the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-01-31 US claimed
US-6986794-B2 Composition of the dyeing of human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-01-17 US claimed
EP-1428502-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2005-10-19 EP claimed
EP-1378228-B1 Composition for the dyeing of human hair KPSS KAO GMBH (DE) 2005-10-12 EP claimed
EP-1557157-A1 Composition for the dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2005-07-27 EP claimed
US-20040139561-A1 Composition of the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2004-07-22 US claimed
EP-1428502-A2 Composition for the dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-06-16 EP claimed
EP-1428503-A2 Composition for the dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-06-16 EP claimed
US-20040107514-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2004-06-10 US claimed
US-20040003474-A1 Composition for the dyeing of human hair KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2004-01-08 US claimed
EP-1378228-A1 Composition for the dyeing of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2004-01-07 EP claimed
US-4125367-A FOR KERATINIC FIBERS L'OREAL (FR) 1978-11-14 US claimed
EP-3480224-A1 ELECTRO-OPTIC POLYMER National Institute of Information and Communications Technology (JP) 2019-05-08 EP disclosed
CN-106483174-A A kind of method of poly- curcumin nickel carbon nanotube paste electrode Electrochemical Detection Neosynephrine 广西民族师范学院 2017-03-08 CN disclosed
US-RE30199-E Oxidation hair dyes based upon tetraaminopyrimidine developers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1980-01-29 US disclosed
US-4125367-A FOR KERATINIC FIBERS L'OREAL (FR) 1978-11-14 US disclosed
US-4003699-A Oxidation hair dyes based upon tetraaminopyrimidine developers HENKEL & CIE G.M.B.H. (DT) 1977-01-18 US disclosed