Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842587 | 0.80 | ALDH1A1 (0.33) | KDM4EALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL1839700 | 0.78 | ALDH1A1 (0.34) | KDM4EALDH1A1TSHR | |
| SCHEMBL5145534 | 0.77 | HRH3 (0.39) | JAK2HRH4HTR1ADRD2HRH3 | |
| SCHEMBL5143549 | 0.73 | KMT2A (0.38) | ELANEKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL5145189 | 0.72 | MAP4K4 (0.39) | PDE2AKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL15291889 | 0.68 | JAK2 (0.40) | MAP4K4MAPK8BTKMRGPRX2MAPK10 | |
| SCHEMBL21859796 | 0.68 | PIM1 (0.41) | ELANEKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL10118590 | 0.67 | MAP4K4 (0.36) | PDE2AMAP4K4MAPK8BTKMRGPRX2 | |
| SCHEMBL13016513 | 0.67 | LMNA (0.34) | PDE2AKDM4EALDH1A1TSHR | |
| SCHEMBL22652021 | 0.66 | KCNH2 (0.43) | MAP4K4USP28HTR6HRH3MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | claimed |
| WO-2012084472-A1 | PROCESS FOR DYEING KERATIN FIBRES USING HYDROXYBENZALDEHYDE DERIVATIVES, OXIDIZING AGENTS AND ALKALINIZING AGENTS IN THE PRESENCE OF HEAT | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012084472-A1 | PROCESS FOR DYEING KERATIN FIBRES USING HYDROXYBENZALDEHYDE DERIVATIVES, OXIDIZING AGENTS AND ALKALINIZING AGENTS IN THE PRESENCE OF HEAT | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| EP-1792606-B1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | OREAL (FR) | 2011-05-18 | — | — | EP | disclosed |
| US-7857864-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivative | L'OREAL S.A. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-7857864-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivative | L'OREAL S.A. (FR) | 2010-12-28 | — | — | US | disclosed |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | L'OREAL S.A. (FR) | 2010-05-13 | — | — | US | disclosed |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | L'OREAL S.A. (FR) | 2010-05-13 | — | — | US | disclosed |
| US-7635394-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2009-12-22 | — | — | US | disclosed |
| US-7635394-B2 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2009-12-22 | — | — | US | disclosed |
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2007-06-28 | — | — | US | disclosed |
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | L'OREAL S.A. (FR) | 2007-06-28 | — | — | US | disclosed |
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | disclosed |
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070143935-A1 | Composition for the dyeing of keratin fibers comprising at least one 3-amino-pyrazolopyridine derivatives | KRT18, MARK1, MARK2 | PDE2A 922/4885ELANE 3028/4885KDM4E 1442/4885 |
| US-20100115711-A1 | COMPOSITION FOR THE DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE 3-AMINO-PYRAZOLOPYRIDINE DERIVATIVE | KRT18, MARK1, MARK2 | PDE2A 968/4885ELANE 3025/4885KDM4E 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.