Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 9/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31172118 | 0.83 | SLC6A2 (0.52) | SLC6A2TAAR1CA2CA1CA12 | |
| SCHEMBL9131072 | 0.82 | CA2 (0.53) | SLC6A2TAAR1CA2SMN1; SMN2 | |
| SCHEMBL31275754 | 0.81 | CA1 (0.46) | CA2CA1CA12CA14CA9 | |
| SCHEMBL6726913 | 0.81 | SLC6A2 (0.50) | SLC6A2TAAR1CA2CA1CA12 | |
| SCHEMBL25245166 | 0.80 | CA2 (0.44) | TAAR1CA2CA1CA12CA7 | |
| SCHEMBL6726914 | 0.79 | SLC6A2 (0.48) | SLC6A2TAAR1CA2CA1LMNA | |
| SCHEMBL5700047 | 0.79 | SLC6A2 (0.48) | SLC6A2TAAR1CA2CA1CA12 | |
| SCHEMBL9085340 | 0.79 | CA2 (0.56) | CA2CA1CA12CA7CA14 | |
| SCHEMBL3838424 | 0.79 | SLC6A2 (0.48) | SLC6A2TAAR1CA2CA1CA12 | |
| SCHEMBL28458665 | 0.77 | CA1 (0.54) | TAAR1CA2CA1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663113-A4 | SUBSTITUTED SULFONAMIDES | MERCK & CO INC (US) | 2007-06-13 | — | — | EP | claimed |
| EP-1663113-A2 | SUBSTITUTED SULFONAMIDES | Merck & Co., Inc. (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2005027837-A2 | SUBSTITUTED SULFONAMIDES | MERCK & CO., INC. (US) | 2005-03-31 | — | — | WO | claimed |
| EP-2192631-A1 | PROCESS FOR PRODUCTION OF DESUBSTITUTED COMPOUNDS, ORGANIC SEMICONDUCTOR FILM AND PROCESS FOR PRODUCTION OF THE FILM | Fujifilm Corporation (JP) | 2010-06-02 | — | — | EP | disclosed |