Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TDO2 | P48775 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | CASP6 | P55212 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29439822 | 0.75 | GALR3 (0.39) | MAPTGRM4KMT2AHPGDLMNA | |
| SCHEMBL18130786 | 0.75 | GALR3 (0.39) | MAPTGRM4KMT2AHPGDLMNA | |
| SCHEMBL30071547 | 0.73 | KDM4E (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL342380 | 0.73 | KDM4E (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL30856584 | 0.72 | MAPT (0.44) | PDE10AMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3790051 | 0.72 | MAPT (0.44) | PDE10AMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11546073 | 0.72 | GRM4 (0.35) | MAPTGRM4ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28220934 | 0.71 | KDM4E (0.47) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3169007 | 0.69 | PDE10A (0.53) | PDE10AMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1253994 | 0.69 | NOS1 (0.50) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976597-B1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2024-08-28 | — | — | EP | disclosed |
| JP-5324040-B2 | — | — | 2013-10-23 | — | — | JP | disclosed |
| EP-1792606-A1 | Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine | L'Oréal (FR) | 2007-06-06 | — | — | EP | disclosed |
| EP-1792903-A1 | Composition for the dyeing of keratin fibres comprising at least one cationic 3-amino-pyrazolopyridine derivative | L'OREAL (FR) | 2007-06-06 | — | — | EP | disclosed |