SCHEMBL514524

SCHEMBL514524

C=CC(=O)NCC(OC)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
TSHR P16473 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
MAPK1 P28482 2/20 0.48
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
GFPT1 Q06210 1/20 0.36
TGM2 P21980 2/20 0.34
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
LMNA P02545 1/20 0.33
KDM4E B2RXH2 2/20 0.32
GLA P06280 1/20 0.32
MAPT P10636 1/20 0.32
GAA P10253 1/20 0.32
PSMB11 A5LHX3 1/20 0.32
PSMA7 O14818 1/20 0.32
PSMB1 P20618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18685005 0.87 TSHR (0.41) ALDH1A1TSHRTDP1MAPK1ZDHHC20
SCHEMBL1082115 0.87 ZDHHC20 (0.47) ALDH1A1TSHRTDP1MAPK1ZDHHC20
SCHEMBL18755020 0.83 TSHR (0.48) ALDH1A1TSHRTDP1MAPK1ZDHHC20
SCHEMBL24492302 0.82 TSHR (0.46) ALDH1A1TSHRTDP1MAPK1ZDHHC20
SCHEMBL29042187 0.82 TSHR (0.46) ALDH1A1TSHRTDP1MAPK1ZDHHC20
SCHEMBL24492417 0.82 TSHR (0.46) ALDH1A1TSHRTDP1MAPK1ZDHHC20
SCHEMBL12313610 0.82 TSHR (0.46) ALDH1A1TSHRTDP1MAPK1ZDHHC20
SCHEMBL19619516 0.80 TSHR (0.45) ALDH1A1TSHRTDP1MAPK1ZDHHC20
SCHEMBL3288459 0.80 ZDHHC20 (0.47) ALDH1A1TSHRTDP1MAPK1ZDHHC20
SCHEMBL19928434 0.80 TSHR (0.45) ALDH1A1TSHRTDP1MAPK1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117982687-A Imageable embolic microspheres 生物兼容英国有限公司 2024-05-07 CN claimed
CN-116675879-A Injectable antibacterial conductive hydrogel 河北工业大学 2023-09-01 CN claimed
CN-115779135-A Method and reaction device for preparing particle size controllable high-purity polyvinyl alcohol embolism microspheres 海南百迈科医疗科技股份有限公司 2023-03-14 CN claimed
EP-4000639-A1 IMAGEABLE POLYMERS Biocompatibles Uk Ltd. (GB) 2022-05-25 EP claimed
CN-110219204-B Moisture-resistant dry strength agent for kraft paper and preparation method thereof 南昌市龙然实业有限公司 2021-12-07 CN claimed
US-20210236660-A1 IMAGEABLE POLYMERS BIOCOMPATIBLES UK LTD. 2021-08-05 US claimed
CN-110201215-B Gradient cross-linked high-elasticity embolism microsphere and preparation process thereof 科睿驰(深圳)医疗科技发展有限公司 2021-07-30 CN claimed
CN-106729953-B Functionalized modified polyvinyl alcohol embolism microsphere and preparation method thereof 苏州恒瑞迦俐生生物医药科技有限公司 2020-09-15 CN claimed
CN-111569144-A Medicine-carrying embolism microsphere with developing function and preparation method thereof 科睿驰(深圳)医疗科技发展有限公司 2020-08-25 CN claimed
CN-110327300-B Drug-loaded polyvinyl alcohol microspheres 赵修文 2020-08-07 CN claimed
US-20050082024-A1 Temporary wet strength additives THE PROCTER & GAMBLE COMPANY 2005-04-21 US claimed
US-20050082023-A1 Temporary wet strength resins THE PROCTER & GAMBLE COMPANY 2005-04-21 US claimed
US-20050025741-A1 Copolymers with (meth)acrylamides; improved separation of polynucleotides APPLIED BIOSYSTEMS, LLC 2005-02-03 US claimed
WO-2004104054-A1 POLY AND COPOLY (N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS APPLERA CORPORATION (US) 2004-12-02 WO claimed
WO-2004071495-A1 COMPOSITION FOR CHEMOEMBOLOTHERAPY OF SOLID TUMORS BIOCOMPATIBLES UK LIMITED (GB) 2004-08-26 WO claimed
US-20040161466-A1 Chemoembolisation BIOCOMPATIBLES UK LIMITED 2004-08-19 US claimed
WO-2004011513-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS APPLERA CORPORATION (US) 2004-02-05 WO claimed
EP-0915918-A1 RESINS OF AMPHOTERIC ALDEHYDE POLYMERS AND USE OF SAID RESINS AS TEMPORARY WET-STRENGTH OR DRY-STRENGTH RESINS FOR PAPER HERCULES INCORPORATED (US) 1999-05-19 EP claimed
WO-1998054237-A1 RESINS OF AMPHOTERIC ALDEHYDE POLYMERS AND USE OF SAID RESINS AS TEMPORARY WET-STRENGTH OR DRY-STRENGTH RESINS FOR PAPER HERCULES INCORPORATED (US) 1998-12-03 WO claimed
US-5138002-A Temporary wet strength resins with nitrogen heterocyclic nonnucleophilic functionalities and paper products containing same THE PROCTER & GAMBLE COMPANY (US) 1992-08-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040161466-A1 Chemoembolisation VHL, POLH, POLQ ALDH1A1 2095/4885TSHR 4121/4885TDP1 2045/4885
US-20210236660-A1 IMAGEABLE POLYMERS VHL, FLT4, FLT1 ALDH1A1 2674/4885TSHR 2564/4885TDP1 2037/4885
US-20050025741-A1 Copolymers with (meth)acrylamides; improved separation of polynucleotides POLI, PCNA, POLL ALDH1A1 3357/4885TSHR 4259/4885TDP1 337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.