SCHEMBL5145373

SCHEMBL5145373

O=C(Nc1cc(Br)ccc1C(=O)O)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACLY P53396 1/20 0.71
MEN1 O00255 4/20 0.68
KMT2A Q03164 4/20 0.68
MAPT P10636 3/20 0.68
GRIK1 P39086 2/20 0.68
PKM P14618 2/20 0.68
TDP1 Q9NUW8 2/20 0.68
KCNK2 O95069 2/20 0.67
KCNK10 P57789 2/20 0.67
DHODH Q02127 2/20 0.63
AKR1C4 P17516 1/20 0.61
AKR1C3 P42330 1/20 0.61
AKR1C2 P52895 1/20 0.61
AKR1C1 Q04828 1/20 0.61
NR1H4 Q96RI1 1/20 0.57
ABL1 P00519 1/20 0.57
TSHR P16473 1/20 0.57
RIN1 Q13671 1/20 0.57
ALDH1A1 P00352 1/20 0.56
KDM4D Q6B0I6 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674689 0.89 MAPT (0.64) ACLYMEN1KMT2AMAPTGRIK1
SCHEMBL14428469 0.88 MAPT (0.62) ACLYMEN1KMT2AMAPTGRIK1
SCHEMBL9513479 0.87 MAPT (0.80) MEN1KMT2AMAPTGRIK1PKM
SCHEMBL18343780 0.86 EPHX1 (0.62) ACLYMEN1KMT2AMAPTKCNK2
SCHEMBL2275624 0.85 KDM4E (0.64) ACLYMEN1KMT2AMAPTGRIK1
SCHEMBL16936176 0.83 HDAC1 (0.71) ACLYMEN1KMT2AMAPTGRIK1
SCHEMBL21931016 0.83 ACLY (1.00) ACLYMEN1KMT2AMAPTGRIK1
SCHEMBL637477 0.82 KMT2A (0.70) ACLYMEN1KMT2AMAPTGRIK1
SCHEMBL2271365 0.82 PKM (0.70) ACLYMEN1KMT2AMAPTGRIK1
SCHEMBL1307525 0.82 DHODH (0.74) MEN1KMT2AMAPTPKMKCNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed