SCHEMBL5145407

SCHEMBL5145407

O=C(Nc1cc(COc2ccccc2)ccc1C(=O)O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.59
KMT2A Q03164 8/20 0.59
NPC1 O15118 6/20 0.59
RAB9A P51151 6/20 0.59
RXFP1 Q9HBX9 2/20 0.59
LTC4S Q16873 1/20 0.59
SMN1; SMN2 Q16637 3/20 0.57
MAPT P10636 2/20 0.56
PKM P14618 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
GRIK1 P39086 1/20 0.56
ALDH1A1 P00352 1/20 0.55
NR1H4 Q96RI1 3/20 0.54
CASP3 P42574 1/20 0.53
TAAR1 Q96RJ0 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
LMNA P02545 1/20 0.53
PLK1 P53350 1/20 0.52
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2275889 0.89 KDM4E (0.61) MEN1KMT2ANPC1RAB9ARXFP1
SCHEMBL2275173 0.87 SMN1; SMN2 (0.63) MEN1KMT2ANPC1RAB9ARXFP1
SCHEMBL2290164 0.81 SMN1; SMN2 (0.76) MEN1KMT2ANPC1RAB9ARXFP1
SCHEMBL2271422 0.81 LTC4S (0.74) MEN1KMT2ALTC4SMAPTPKM
SCHEMBL2275929 0.81 KMT2A (0.62) MEN1KMT2ALTC4SMAPTPKM
SCHEMBL2278451 0.80 LTC4S (0.60) MEN1KMT2ALTC4SMAPTPKM
SCHEMBL2364639 0.79 ABCB1 (0.65) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL2295551 0.79 NPC1 (0.71) MEN1KMT2ANPC1RAB9ARXFP1
SCHEMBL2271236 0.78 PLK1 (0.60) MEN1KMT2ANPC1RAB9ALTC4S
SCHEMBL2272409 0.78 PLK1 (0.63) MEN1KMT2ANPC1RAB9ALTC4S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101094829-B novel anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO.,LTD. (JP) 2012-02-08 CN disclosed
CN-101094829-A Novel anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO LTD (JP) 2007-12-26 CN disclosed
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed