Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL5145485

CCCCc1ccccc1Oc1ccccc1CCCC.OCCOCCO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
THRB P10828 2/20 0.43
THRA P10827 1/20 0.43
ALOX5 P09917 1/20 0.43
PTGS2 P35354 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 2/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
CASP1 P29466 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
SLCO1B3 Q9NPD5 1/20 0.42
SLCO1B1 Q9Y6L6 1/20 0.42
HTT P42858 1/20 0.42
MAPT P10636 1/20 0.42
NPSR1 Q6W5P4 1/20 0.40
LIPG Q9Y5X9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraethylene Glycol SCHEMBL5143708 0.98 MEN1 (0.44) TSHRTHRBTHRAALOX5PTGS2
Triethylene Glycol SCHEMBL5143985 0.98 MEN1 (0.44) TSHRTHRBTHRAALOX5PTGS2
Di(Hydroxyethyl)Ether SCHEMBL7263984 0.94 THRB (0.51) TSHRTHRBTHRAALOX5PTGS2
Di(Hydroxyethyl)Ether SCHEMBL5144171 0.94 THRB (0.51) TSHRTHRBTHRAALOX5PTGS2
Di(Hydroxyethyl)Ether SCHEMBL5144100 0.94 THRB (0.51) TSHRTHRBTHRAALOX5PTGS2
Triethylene Glycol SCHEMBL11002434 0.92 MEN1 (0.52) TSHRTHRBTHRAALOX5PTGS2
Triethylene Glycol SCHEMBL5142014 0.92 MEN1 (0.52) TSHRTHRBTHRAALOX5PTGS2
Tetraethylene Glycol SCHEMBL5143759 0.92 MEN1 (0.52) TSHRTHRBTHRAALOX5PTGS2
Tetraethylene Glycol SCHEMBL5145447 0.92 MEN1 (0.52) TSHRTHRBTHRAALOX5PTGS2
Triethylene Glycol SCHEMBL5144067 0.92 MEN1 (0.52) TSHRTHRBTHRAALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3770154-B1 GLYCOLIDE PRODUCTION METHOD KUREHA CORP (JP) 2025-02-19 EP disclosed
US-20240182397-A1 METHOD FOR PRODUCING GLYCOLIDE KUREHA CORPORATION (JP) 2024-06-06 US disclosed
EP-4310078-A1 METHOD FOR PRODUCING GLYCOLIDE Kureha Corporation (JP) 2024-01-24 EP disclosed
CN-116897151-A Process for producing glycolide 株式会社吴羽 2023-10-17 CN disclosed
US-11753391-B2 Method for producing glycolide KUREHA CORPORATION (JP) 2023-09-12 US disclosed
CN-111741952-B Process for producing glycolide 株式会社吴羽 2023-06-09 CN disclosed
EP-3770153-B1 METHOD FOR PRODUCING GLYCOLIDE KUREHA CORP (JP) 2022-12-28 EP disclosed
WO-2022196178-A1 METHOD FOR PRODUCING GLYCOLIDE 株式会社クレハ 2022-09-22 WO disclosed
US-11078179-B2 Method for producing cyclic ester KUREHA CORPORATION (JP) 2021-08-03 US disclosed
US-11046665-B2 Method for producing α-hydroxycarboxylic acid dimeric cyclic ester KUREHA CORPORATION (JP) 2021-06-29 US disclosed
US-7235673-B2 Glycolide production process, and glycolic acid oligomer for glycolide production KUREHA CORPORATION (JP) 2007-06-26 US disclosed
EP-1366037-B1 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID COMPOSITION KUREHA CHEMICAL IND CO LTD (JP) 2005-08-24 EP disclosed
US-6891048-B2 Glycolide production process, and glycolic acid composition KUREHA KAGAKU KOGYO KK (JP) 2005-05-10 US disclosed
EP-1377566-B1 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID OLIGOMER FOR GLYCOLIDE PRODUCTION KUREHA CHEMICAL IND CO LTD (JP) 2004-09-22 EP disclosed
US-20040122240-A1 Glycolide production process, and glycolic acid oligomer for glycolide production KUREHA CORPORATION (JP) 2004-06-24 US disclosed
US-20040087805-A1 Glycolide production process, and glycolic acid composition KUREHA CORPORATION (JP) 2004-05-06 US disclosed
EP-1377566-A1 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID OLIGOMER FOR GLYCOLIDE PRODUCTION Kureha Chemical Industry Co., Ltd. (JP) 2004-01-07 EP disclosed
EP-1366037-A2 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID COMPOSITION KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2003-12-03 EP disclosed
WO-2002083661-A1 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID OLIGOMER FOR GLYCOLIDE PRODUCTION KUREHA CHEMICAL INDUSTRY COMPANY, LIMITED (JP) 2002-10-24 WO disclosed
WO-2002070508-A2 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID COMPOSITION KUREHA KAGAKU KOGYO K.K. (JP) 2002-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087805-A1 Glycolide production process, and glycolic acid composition DDOST, DAD1, AGL TSHR 4146/4885THRB 4303/4885THRA 3545/4885
US-11078179-B2 Method for producing cyclic ester SCD, DECR2, PDIA4 TSHR 4594/4885THRB 4701/4885THRA 4023/4885
US-20040122240-A1 Glycolide production process, and glycolic acid oligomer for glycolide production UGCG, DAD1, DDOST TSHR 3185/4885THRB 3898/4885THRA 3149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.