SCHEMBL5145487

SCHEMBL5145487

CCCCc1ccccc1OCCOCCO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
LMNA P02545 2/20 0.50
USP2 O75604 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPK1 P28482 1/20 0.50
CASP1 P29466 1/20 0.50
SLCO1B3 Q9NPD5 1/20 0.50
SLCO1B1 Q9Y6L6 1/20 0.50
MAPT P10636 2/20 0.45
NPSR1 Q6W5P4 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KDM4E B2RXH2 2/20 0.44
LTB4R Q15722 1/20 0.44
LTB4R2 Q9NPC1 1/20 0.44
PPARD Q03181 1/20 0.44
THRB P10828 2/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5143987 1.00 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL5143710 1.00 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL7263986 0.94 MEN1 (0.58) ALDH1A1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL6855044 0.94 MEN1 (0.58) ALDH1A1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL7892842 0.94 MEN1 (0.58) ALDH1A1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL2169348 0.94 MEN1 (0.58) ALDH1A1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL10414494 0.94 MEN1 (0.58) ALDH1A1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL10581916 0.94 MEN1 (0.58) ALDH1A1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL5145456 0.94 MEN1 (0.58) ALDH1A1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL1741013 0.94 MEN1 (0.58) ALDH1A1SMN1; SMN2KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3770154-B1 GLYCOLIDE PRODUCTION METHOD KUREHA CORP (JP) 2025-02-19 EP disclosed
US-20240182397-A1 METHOD FOR PRODUCING GLYCOLIDE KUREHA CORPORATION (JP) 2024-06-06 US disclosed
EP-4310078-A1 METHOD FOR PRODUCING GLYCOLIDE Kureha Corporation (JP) 2024-01-24 EP disclosed
CN-116897151-A Process for producing glycolide 株式会社吴羽 2023-10-17 CN disclosed
US-11753391-B2 Method for producing glycolide KUREHA CORPORATION (JP) 2023-09-12 US disclosed
CN-111741952-B Process for producing glycolide 株式会社吴羽 2023-06-09 CN disclosed
EP-3770153-B1 METHOD FOR PRODUCING GLYCOLIDE KUREHA CORP (JP) 2022-12-28 EP disclosed
WO-2022196178-A1 METHOD FOR PRODUCING GLYCOLIDE 株式会社クレハ 2022-09-22 WO disclosed
US-11078179-B2 Method for producing cyclic ester KUREHA CORPORATION (JP) 2021-08-03 US disclosed
US-11046665-B2 Method for producing α-hydroxycarboxylic acid dimeric cyclic ester KUREHA CORPORATION (JP) 2021-06-29 US disclosed
US-7235673-B2 Glycolide production process, and glycolic acid oligomer for glycolide production KUREHA CORPORATION (JP) 2007-06-26 US disclosed
EP-1366037-B1 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID COMPOSITION KUREHA CHEMICAL IND CO LTD (JP) 2005-08-24 EP disclosed
US-6891048-B2 Glycolide production process, and glycolic acid composition KUREHA KAGAKU KOGYO KK (JP) 2005-05-10 US disclosed
EP-1377566-B1 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID OLIGOMER FOR GLYCOLIDE PRODUCTION KUREHA CHEMICAL IND CO LTD (JP) 2004-09-22 EP disclosed
US-20040122240-A1 Glycolide production process, and glycolic acid oligomer for glycolide production KUREHA CORPORATION (JP) 2004-06-24 US disclosed
US-20040087805-A1 Glycolide production process, and glycolic acid composition KUREHA CORPORATION (JP) 2004-05-06 US disclosed
EP-1377566-A1 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID OLIGOMER FOR GLYCOLIDE PRODUCTION Kureha Chemical Industry Co., Ltd. (JP) 2004-01-07 EP disclosed
EP-1366037-A2 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID COMPOSITION KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2003-12-03 EP disclosed
WO-2002083661-A1 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID OLIGOMER FOR GLYCOLIDE PRODUCTION KUREHA CHEMICAL INDUSTRY COMPANY, LIMITED (JP) 2002-10-24 WO disclosed
WO-2002070508-A2 GLYCOLIDE PRODUCTION PROCESS, AND GLYCOLIC ACID COMPOSITION KUREHA KAGAKU KOGYO K.K. (JP) 2002-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087805-A1 Glycolide production process, and glycolic acid composition DDOST, DAD1, AGL ALDH1A1 3923/4885SMN1; SMN2 2939/4885KMT2A 4398/4885
US-11078179-B2 Method for producing cyclic ester SCD, DECR2, PDIA4 ALDH1A1 1037/4885SMN1; SMN2 1616/4885KMT2A 3681/4885
US-20040122240-A1 Glycolide production process, and glycolic acid oligomer for glycolide production UGCG, DAD1, DDOST ALDH1A1 1400/4885SMN1; SMN2 4695/4885KMT2A 4761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.