Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345057 | 0.75 | TRPA1 (0.43) | TSHRCYP3A4ALOX15TAAR1HTR2A | |
| SCHEMBL577034 | 0.75 | LMNA (0.50) | TSHRCYP3A4ALOX15TAAR1HTR2A | |
| SCHEMBL575678 | 0.75 | TSHR (0.39) | TSHRCYP3A4ALOX15TAAR1HTR2A | |
| SCHEMBL8094192 | 0.73 | SLC6A2 (0.47) | TSHRCYP3A4TAAR1KDM4ENPSR1 | |
| SCHEMBL9728549 | 0.73 | HTR2A (0.52) | TSHRTAAR1HTR2ATDP1DPP4 | |
| SCHEMBL11389632 | 0.71 | TAAR1 (0.42) | TSHRCYP3A4ALOX15TAAR1HTR2A | |
| SCHEMBL775566 | 0.71 | AOC3 (0.44) | TSHRCYP3A4ALOX15TAAR1HTR2A | |
| SCHEMBL28573610 | 0.71 | TRPA1 (0.47) | TSHRCYP3A4ALOX15TAAR1HTR2A | |
| SCHEMBL8727413 | 0.71 | HRH1 (0.38) | TSHRCYP3A4ALOX15TAAR1HTR2A | |
| SCHEMBL5598365 | 0.70 | TSHR (0.48) | TSHRCYP3A4ALOX15TAAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7303863-B2 | Silver halide emulsion and silver halide photographic light-sensitive material | FUJIFILM CORPORATION (JP) | 2007-12-04 | — | — | US | disclosed |
| US-20060188829-A1 | Silver halide emulsion and silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. | 2006-08-24 | — | — | US | disclosed |
| EP-0271059-B1 | 2-Methylthiomethyl-dihydropyridines, a process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-10-20 | — | — | EP | disclosed |
| US-4971984-A | Cardiovascular disorders, hypotensive agints | BEEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1990-11-20 | — | — | US | disclosed |
| EP-0271059-A1 | 2-Methylthiomethyl-dihydropyridines, a process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1988-06-15 | — | — | EP | disclosed |
| US-3988375-A | HERBICIDES | MONSANTO COMPANY (US) | 1976-10-26 | — | — | US | disclosed |
| US-3988375-A | HERBICIDES | MONSANTO COMPANY (US) | 1976-10-26 | — | — | US | disclosed |
| US-3946071-A | HERBICIDES | MONSANTO COMPANY (US) | 1976-03-23 | — | — | US | disclosed |