SCHEMBL5145691

SCHEMBL5145691

CC(C)C(C)(CCc1ccccc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 2/20 0.44
KMT2A Q03164 5/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
CYP2D6 P10635 2/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
KEAP1 Q14145 1/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX12 P18054 1/20 0.42
GRM2 Q14416 1/20 0.42
GRM3 Q14832 1/20 0.42
MEN1 O00255 4/20 0.41
HTT P42858 2/20 0.41
HPGD P15428 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3271039 0.85 SMN1; SMN2 (0.43) ALDH1A1TSHRKMT2ACYP2C9CYP2C19
SCHEMBL4226439 0.83 PTPRC (0.43) ALDH1A1TSHRKMT2ACYP2C9CYP2C19
SCHEMBL3268589 0.81 HIF1A (0.50) ALDH1A1TSHRCYP2C9CYP2C19NPC1
SCHEMBL29037265 0.78 POLB (0.43) ALDH1A1TSHRKMT2ACYP2C9CYP2C19
SCHEMBL30080837 0.77 CYP1A2 (0.51) ALDH1A1KMT2ACYP2C9NPC1RAB9A
SCHEMBL5475208 0.77 ALDH1A1 (0.50) ALDH1A1KMT2ANPC1RAB9APOLB
SCHEMBL6628038 0.77 ALDH1A1 (0.50) ALDH1A1KMT2ANPC1RAB9APOLB
SCHEMBL6632235 0.77 ALDH1A1 (0.50) ALDH1A1KMT2ANPC1RAB9APOLB
SCHEMBL173883 0.77 CYP1A2 (0.51) ALDH1A1KMT2ACYP2C9NPC1RAB9A
SCHEMBL12238613 0.76 TRPA1 (0.43) ALDH1A1TSHRKMT2ACYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689848-B Fragrance composition 奇华顿股份有限公司 2022-12-23 CN disclosed
US-20150216182-A1 COMPOSITIONS AND METHODS OF THE ATTRACTION AND REPULSION OF INSECTS OLFACTOR LABORATORIES, INC. 2015-08-06 US disclosed
EP-1797025-A1 4-ISOAMYLCYCLOHEXANOL AS ODIFERANT Symrise GmbH & Co. KG (DE) 2007-06-20 EP disclosed
EP-1797026-A1 (Z)-8-CYCLOHEPTADECENE-1-ONE USED AS A PERFUME Symrise GmbH & Co. KG (DE) 2007-06-20 EP disclosed
US-20070088508-A1 Cocrystallization methods APTUIT (WEST LAFAYETTE), LLC 2007-04-19 US disclosed
WO-2007038524-A2 COCRYSTALLIZATION METHODS SSCI, INC. (US) 2007-04-05 WO disclosed
WO-2007009982-A1 4-ISOAMYLCYCLOHEXANONE AS A PERFUME SYMRISE GMBH & CO. KG (DE) 2007-01-25 WO disclosed
WO-2006035010-A1 4-ISOAMYLCYCLOHEXANOL AS ODIFERANT SYMRISE GMBH & CO. KG (DE) 2006-04-06 WO disclosed
WO-2006032665-A1 (Z)-8-CYCLOHEPTADECENE-1-ONE USED AS A PERFUME SYMRISE GMBH & CO. KG (DE) 2006-03-30 WO disclosed
EP-0000771-B1 2,5,7-TRIMETHYLOCTANE-3-OL AND 2,4-DIMETHYLNONANE-8-OL; PROCESSES FOR THEIR PREPARATION; THEIR USE AS OLFACTORY AGENTS; OLFACTORY COMPOSITIONS CONTAINING THEM, AS WELL AS THE PREPARATION OF SUCH OLFACTORY COMPOSITIONS L. Givaudan & Cie Société Anonyme (CH) 1981-09-16 EP disclosed
EP-0000771-A2 2,5,7-Trimethyloctane-3-ol and 2,4-dimethylnonane-8-ol; processes for their preparation; their use as olfactory agents; olfactory compositions containing them, as well as the preparation of such olfactory compositions L. Givaudan & Cie Société Anonyme (CH) 1979-02-21 EP disclosed