SCHEMBL514571

SCHEMBL514571

COC(=O)Nc1ccc(C)cc1

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.69
TDP1 Q9NUW8 1/20 0.61
POLB P06746 1/20 0.59
HPGD P15428 2/20 0.59
MAPT P10636 2/20 0.58
ALDH1A1 P00352 1/20 0.58
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
KIF11 P52732 1/20 0.53
TGM2 P21980 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609808 0.91 SMN1; SMN2 (0.82) SMN1; SMN2POLBHPGDMAPTALDH1A1
SCHEMBL13647687 0.89 SMN1; SMN2 (0.56) SMN1; SMN2TDP1POLBHPGDMAPT
SCHEMBL12444551 0.84 SMN1; SMN2 (0.66) SMN1; SMN2TDP1HPGDMAPTALDH1A1
SCHEMBL12444549 0.84 ALDH1A1 (0.55) SMN1; SMN2TDP1HPGDMAPTALDH1A1
Urethane SCHEMBL10734046 0.84 SMN1; SMN2 (0.54) SMN1; SMN2POLBHPGDMAPTALDH1A1
SCHEMBL7251623 0.84 SMN1; SMN2 (0.72) SMN1; SMN2POLBHPGDMAPTALDH1A1
SCHEMBL13186583 0.83 LMNA (0.78) SMN1; SMN2POLBHPGDMAPTALDH1A1
SCHEMBL6790845 0.83 TDP1 (0.57) SMN1; SMN2TDP1POLBMAPTALDH1A1
SCHEMBL514570 0.83 TDP1 (0.57) SMN1; SMN2TDP1POLBMAPTALDH1A1
SCHEMBL18814226 0.82 SMN1; SMN2 (1.00) SMN1; SMN2TDP1POLBHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462429-A Method for synthesizing amino-methyl-phenyl methyl carbamate compound from p-toluidine 河北工业大学 2025-02-18 CN claimed
CN-103562198-B There is muscarinic receptor antagonist and the compound of beta 2-adrenergic receptor agonists activity 奇斯药制品公司 2016-08-24 CN claimed
CN-103562198-A Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity CHIESI FARMA SPA 2014-02-05 CN claimed
US-20250188021-A1 PREPARATION METHOD FOR ALICYCLIC CARBAMATE AND USE THEREOF INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) 2025-06-12 US disclosed
CN-119462429-A Method for synthesizing amino-methyl-phenyl methyl carbamate compound from p-toluidine 河北工业大学 2025-02-18 CN disclosed
CN-117362188-A Synthesis method of alpha-substituted deuterated amino acid ester 广州医科大学 2024-01-09 CN disclosed
CN-117242060-A Isoindolinone compounds 蒙特罗萨医疗公司 2023-12-15 CN disclosed
EP-3628044-B1 PYRROLO[2,3-C]PYRIDINES AND RELATED ANALOGS AS LSD-1 INHIBITORS UNIV MICHIGAN REGENTS (US) 2023-11-22 EP disclosed
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
WO-2023168889-A1 PREPARATION METHOD FOR ALICYCLIC CARBAMATE AND USE THEREOF 中国科学院过程工程研究所 2023-09-14 WO disclosed
WO-2023168889-A1 PREPARATION METHOD FOR ALICYCLIC CARBAMATE AND USE THEREOF 中国科学院过程工程研究所 2023-09-14 WO disclosed
US-4603216-A RUTHENIUM-PHOSPHINE CATALYST CATALYTICA ASSOCIATES (US) 1986-07-29 US disclosed
US-4600797-A NITRATING AN AMINOBENZENE WHICH HAS A PROTECTEDD AMINO GROUP BAYER AKTIENGESELLSCHAFT (DE) 1986-07-15 US disclosed
US-4600793-A Process for the preparation of urethanes CATALYTICA ASSOCIATES (US) 1986-07-15 US disclosed
EP-0157828-A1 PROCESS FOR THE PREPARATION OF URETHANES. CATALYTICA ASSOCIATES (US) 1985-10-16 EP disclosed
WO-1985001285-A1 PROCESS FOR THE PREPARATION OF URETHANES CATALYTICA ASSOCIATES (US) 1985-03-28 WO disclosed
US-4487713-A HEAT TREATMENT WITH TITANIUM, TIN, ANTIMONY OR ZIRCONIUM COMPOUND EXXON RESEARCH & ENGINEERING CO. (US) 1984-12-11 US disclosed
US-4081472-A CATALYTIC, FROM A CARBAMATE MITSUI TOATSU CHEMICALS INC. (JA) 1978-03-28 US disclosed
US-4069240-A GROUP 8 METAL CATALYST UNIROYAL, INC. (US) 1978-01-17 US disclosed
US-3962302-A Production of isocyanates from esters of carbamic acids (urethanes) ATLANTIC RICHFIELD COMPANY (US) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188021-A1 PREPARATION METHOD FOR ALICYCLIC CARBAMATE AND USE THEREOF PAICS, CPS1, JMJD6 SMN1; SMN2 3727/4885TDP1 2180/4885POLB 2021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.