SCHEMBL5145779

SCHEMBL5145779

CCOC(=O)CNc1ccccc1-c1nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.44
ALDH1A1 P00352 7/20 0.43
LMNA P02545 3/20 0.43
ELANE P08246 1/20 0.41
KDM4E B2RXH2 3/20 0.41
HPGD P15428 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
PPID Q08752 1/20 0.40
GAA P10253 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MAPT P10636 1/20 0.39
POLB P06746 1/20 0.38
THRB P10828 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL388673 0.83 PPID (0.40) HTTALDH1A1LMNAELANEHPGD
SCHEMBL388905 0.83 HTT (0.44) HTTALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL393365 0.81 ALDH1A1 (0.41) HTTALDH1A1LMNAELANEKDM4E
SCHEMBL391448 0.81 LMNA (0.43) ALDH1A1LMNAHPGDSMN1; SMN2PPID
SCHEMBL392049 0.78 HTT (0.44) HTTALDH1A1LMNAKDM4EHPGD
SCHEMBL389280 0.78 LMNA (0.42) HTTALDH1A1LMNAKDM4EHPGD
SCHEMBL388892 0.78 POLB (0.51) HTTALDH1A1LMNAELANEKDM4E
SCHEMBL391281 0.78 ALDH1A1 (0.48) ALDH1A1LMNAKDM4EHPGDSMN1; SMN2
SCHEMBL391288 0.77 LMNA (0.41) HTTALDH1A1LMNAKDM4EHPGD
SCHEMBL393007 0.77 POLB (0.43) HTTALDH1A1LMNAELANEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1865030-A1 DYE-CONTAINING HARDENABLE COMPOSITION, AND COLOR FILTER AND PROCESS FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2007-12-12 EP disclosed
US-20070072096-A1 Negative curable dye-containing composition, color filter, and method of manufacturing the same FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed