SCHEMBL51460

SCHEMBL51460

c1ccc(COc2ccc3ccccc3c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 1.00
CYP3A4 P08684 1/20 0.67
MRGPRX4 Q96LA9 1/20 0.66
NPC1 O15118 4/20 0.59
MAPT P10636 2/20 0.59
AGXT P21549 2/20 0.59
LMNA P02545 1/20 0.59
CYP1A2 P05177 1/20 0.59
PTGS1 P23219 1/20 0.59
SLC6A2 P23975 1/20 0.59
CYP2C19 P33261 1/20 0.59
PTGS2 P35354 1/20 0.59
SLC6A3 Q01959 1/20 0.59
HIF1A Q16665 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
MAOB P27338 4/20 0.58
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
RAB9A P51151 3/20 0.58
MAOA P21397 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8984340 0.96 ALOX5 (0.92) ALOX5CYP3A4MRGPRX4NPC1MAPT
Methyl Alcohol SCHEMBL29235268 0.94 ALOX5 (0.89) ALOX5CYP3A4MRGPRX4NPC1MAPT
SCHEMBL28662350 0.94 ALOX5 (0.89) ALOX5CYP3A4MRGPRX4NPC1MAPT
SCHEMBL1886123 0.91 ALOX5 (0.83) ALOX5CYP3A4MRGPRX4NPC1MAPT
SCHEMBL23483149 0.89 ALOX5 (0.79) ALOX5CYP3A4MRGPRX4NPC1MAPT
SCHEMBL12938497 0.88 ALOX5 (0.78) ALOX5CYP3A4MRGPRX4NPC1MAPT
SCHEMBL3818205 0.87 ALOX5 (0.77) ALOX5CYP3A4MRGPRX4NPC1MAPT
SCHEMBL4629780 0.87 ALOX5 (0.75) ALOX5CYP3A4MRGPRX4NPC1MAPT
SCHEMBL10605167 0.86 ALOX5 (0.76) ALOX5CYP3A4MRGPRX4NPC1MAPT
SCHEMBL9939705 0.86 ALOX5 (0.76) ALOX5CYP3A4MRGPRX4NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2321 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4022391-B1 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2026-03-04 EP claimed
EP-3746309-B1 HEAT-SENSITIVE RECORDING MATERIAL MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2026-01-28 EP claimed
US-12454144-B2 Heat-sensitive recording material comprising phenol-free organic colour developers MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2025-10-28 US claimed
EP-4563366-A1 HEAT-SENSITIVE RECORDING MATERIAL Oji Holdings Corporation (JP) 2025-06-04 EP claimed
CN-119804835-A Static color development testing method for thermosensitive paper 沈阳感光化工研究院有限公司 2025-04-11 CN claimed
CN-114667279-B Thermosensitive recording material containing non-phenolic color developer 索理思科技开曼公司 2025-03-25 CN claimed
US-12151497-B2 Heat sensitive recording material with non-phenolic color developers SOLENIS TECHNOLOGIES, L.P. (US) 2024-11-26 US claimed
CN-118683224-A Blue-black double-color thermosensitive color-developing material 上海马斯夫物联科技有限公司 2024-09-24 CN claimed
CN-118457080-A Multicolor thermosensitive color-developing material 上海瑞年精细化工有限公司 2024-08-09 CN claimed
CN-118403642-A Co@1T/2H-MoS2Catalyst, preparation method and application thereof 山东科技大学 2024-07-30 CN claimed
EP-0573874-A2 Process for the preparation of beta-naphthylbenzylether BASF Aktiengesellschaft (DE) 1993-12-15 EP claimed
EP-0546577-A1 Crystal modification of 2-(3-methylanilino)-3-methyl-6-diethylaminofluoran, process for the preparation thereof, and recording materials containing said crystal modification Yamamoto Chemicals, Inc. (JP) 1993-06-16 EP claimed
US-5135776-A Uniformly dispersing colorless dye and specific heat fusible substance with binder and/or surfactant in water, finely pulverizing with horizontal sand mill, mixing with electron acceptor dispersion, coating on base sheet KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1992-08-04 US claimed
US-5134189-A Isocyanate, Imino Compound, Polymeric Binder MITSUBISHI PAPER MILLS LIMITED (JP) 1992-07-28 US claimed
US-5112798-A Multilayer heat sensitive color forming element to react with a dye precursor, N-methylolbehenic acid amide and a sensitive agent MITSUBISHI PAPER MILLS LIMITED (JP) 1992-05-12 US claimed
EP-0465402-A1 Heat sensitive recording material CIBA-GEIGY AG (CH) 1992-01-08 EP claimed
EP-0422680-A2 Heat-sensitive recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1991-04-17 EP claimed
EP-0405946-A2 Method for producing a heat-sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1991-01-02 EP claimed
US-4889841-A 2-BENZYLOXYNAPHTHALENE AND P-BENZYLBIPHENYL ADDITIVES; NONFOGGING; THERMAL RESPONSE, NONADHERING MITSUBISHI PAPER MILLS LIMITED (JP) 1989-12-26 US claimed
US-4742042-A Thermosensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1988-05-03 US claimed