SCHEMBL514626

SCHEMBL514626

C=C(C)C(N)=O.C=CC(=O)N(C)C

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.55
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
FGFR4 P22455 1/20 0.38
TP53 P04637 1/20 0.33
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL28731521 0.85 ALDH1A1 (0.45) TDP1ALDH1A1TSHRFGFR4LMNA
Methacrylic Acid SCHEMBL3265200 0.84 ALDH1A1 (0.39) TDP1ALDH1A1TSHRTP53LMNA
Acrylamide SCHEMBL21878645 0.84 ALDH1A1 (0.52) TDP1ALDH1A1TSHRFGFR4LMNA
Methacrylic Acid SCHEMBL30438082 0.84 ALDH1A1 (0.39) TDP1ALDH1A1TSHRTP53LMNA
Acrylamide SCHEMBL5555465 0.83 ALDH1A1 (0.58) ALDH1A1TSHRFGFR4LMNA
SCHEMBL15015 0.83
SCHEMBL1049447 0.82 ALDH1A1 (0.38) TDP1ALDH1A1TSHRTP53
Acetic Acid SCHEMBL3875791 0.80 ALDH1A1 (0.45) ALDH1A1TSHRFGFR4TP53LMNA
Ethane SCHEMBL10637100 0.80
Ammonia Solution, Strong SCHEMBL16774831 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10338408-B2 Method for making improved UV-absorbing ophthalmic lenses NOVARTIS AG (CH) 2019-07-02 US claimed
EP-2932314-B1 METHOD FOR MAKING IMPROVED UV-ABSORBING OPHTHALMIC LENSES NOVARTIS AG (CH) 2017-02-01 EP claimed
US-9527251-B2 Composition for manufacturing contact lenses and method for manufacturing contact lenses by using the same BENQ MATERIALS CORPORATION (TW) 2016-12-27 US claimed
US-9505184-B2 Silicone hydrogel lens with a crosslinked hydrophilic coating NOVARTIS AG (CH) 2016-11-29 US claimed
EP-2766750-B1 METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES BY COATING NOVARTIS AG (CH) 2016-02-03 EP claimed
EP-2780748-B1 A SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING NOVARTIS AG (CH) 2016-01-13 EP claimed
EP-2932314-A1 METHOD FOR MAKING IMPROVED UV-ABSORBING OPHTHALMIC LENSES Novartis AG (CH) 2015-10-21 EP claimed
US-9005700-B2 Method for making UV-absorbing ophthalmic lenses NOVARTIS AG (CH) 2015-04-14 US claimed
EP-2780748-A1 A SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING Novartis AG (CH) 2014-09-24 EP claimed
EP-2766750-A1 METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES BY COATING Novartis AG (CH) 2014-08-20 EP claimed
WO-2014095690-A1 METHOD FOR MAKING IMPROVED UV-ABSORBING OPHTHALMIC LENSES NOVARTIS AG (CH) 2014-06-26 WO claimed
US-20140178595-A1 Method for Making Improved UV-Absorbing Ophthalmic Lenses NOVARTIS AG (CH) 2014-06-26 US claimed
WO-2013074535-A1 A SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING NOVARTIS AG (CH) 2013-05-23 WO claimed
US-20130118127-A1 SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING NOVARTIS AG (CH) 2013-05-16 US claimed
US-20130095235-A1 METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES NOVARTIS AG (CH) 2013-04-18 US claimed
WO-2013055746-A1 METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES BY COATING NOVARTIS AG (CH) 2013-04-18 WO claimed
US-4460477-A Use of a carboxylic functional polyampholyte to inhibit the precipitation and deposit of scale in aqueous systems CALGON CORPORATION (US) 1984-07-17 US claimed
EP-2705808-B1 Silicone hydrogel lenses with water-rich surfaces ALCON INC (CH) 2024-05-01 EP disclosed
WO-2004104051-A1 BIMOLECULAR PHOTOINITIATOR SYSTEMS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-12-02 WO disclosed
EP-0819258-B1 EXTENDED WEAR OPHTHALMIC LENS NOVARTIS AG (CH) 2001-09-12 EP disclosed