Methacrylic Acid

Methacrylic Acid

SCHEMBL3265200

C=C(C)C(=O)O.C=CC(=O)N(C)C

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35
LMNA P02545 1/20 0.35
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL30438082 1.00 ALDH1A1 (0.39) ALDH1A1TP53TSHRLMNAALOX15
Acetic Acid SCHEMBL3875791 0.87 ALDH1A1 (0.45) ALDH1A1TP53TSHRLMNA
Methacrylic Acid SCHEMBL6246231 0.85 TGFBR1 (0.33) ALDH1A1LMNA
SCHEMBL15015 0.84
SCHEMBL1049447 0.84 ALDH1A1 (0.38) ALDH1A1TP53TSHRTDP1
SCHEMBL514626 0.84 TDP1 (0.55) ALDH1A1TP53TSHRLMNAALOX15
Acrylic Acid SCHEMBL3951632 0.82 LMNA (0.56) ALDH1A1TSHRLMNAALOX15HSD17B10
SCHEMBL253241 0.82
Methane SCHEMBL10717295 0.82
Ethane SCHEMBL10637100 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8377464-B2 Polymerizable surfactants and their use as device forming comonomers BAUSCH & LOMB INCORPORATED (US) 2013-02-19 US disclosed
US-20120157565-A1 Polymerizable Surfactants and Their Use as Device Forming Comonomers BAUSCH HEALTH US, LLC 2012-06-21 US disclosed
US-8197841-B2 Polymerizable surfactants and their use as device forming comonomers BAUSCH & LOMB INCORPORATED (US) 2012-06-12 US disclosed
EP-2255228-A1 LENSES COMPRISING AMPHIPHILIC MULTIBLOCK COPOLYMERS Bausch & Lomb Incorporated (US) 2010-12-01 EP disclosed
US-20100069522-A1 LENSES COMPRISING AMPHIPHILIC MULTIBLOCK COPOLYMERS HUMAX PHARMACEUTICAL S.A. (CO) 2010-03-18 US disclosed
EP-1828813-B1 POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS BAUSCH & LOMB (US) 2010-02-10 EP disclosed
WO-2009117374-A1 LENSES COMPRISING AMPHIPHILIC MULTIBLOCK COPOLYMERS BAUSCH & LOMB INCORPORATED (US) 2009-09-24 WO disclosed
WO-2008057104-A1 USE OF THERMAL REVERSIBLE ASSOCIATIONS FOR ENHANCED POLYMER INTERACTIONS BAUSCH & LOMB INCORPORATED (US) 2008-05-15 WO disclosed
WO-2007149083-A1 POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS BAUSCH & LOMB INCORPORATED (US) 2007-12-27 WO disclosed
EP-1828813-A1 POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS Bausch & Lomb Incorporated (US) 2007-09-05 EP disclosed
EP-0559784-A1 SURFACE-ACTIVE MACROMONOMERS. BAUSCH & LOMB (US) 1993-09-15 EP disclosed
US-5219965-A Adding polymerizable surfactant to monomer mixture; contact lenses BAUSCH & LOMB INCORPORATED (US) 1993-06-15 US disclosed
US-5177165-A Contact lenses BAUSCH & LOMB INCORPORATED (US) 1993-01-05 US disclosed
US-5135297-A Immersing a contact lens in an aqueous dispersion of a polymerizable surfactant macromer, a crosslinker and a free radical catalyst and irradiating with UV light; wetting agents BAUSCH & LOMB INCORPORATED (US) 1992-08-04 US disclosed
WO-1992009639-A2 SURFACE-ACTIVE MACROMONOMERS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed
WO-1992009650-A1 SURFACE COATING OF POLYMER OBJECTS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed
WO-1992009644-A1 SURFACE MODIFICATION OF POLYMER OBJECTS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed
US-4356109-A POLYMERIZING UREA AND FORMALDEHYDE IN PRESENCE OF ANIONIC POLYELECTROLYTE AND AN AMMONIUM SALT OF AN ACID FUJI PHOTO FILM CO., LTD. (JP) 1982-10-26 US disclosed
US-4251386-A BY POLYMERIZATION OF UREA AND FORMALDEHYDE IN AN ANIONIC POLYELECTROLYTE AND AN AMMONIUM SALT OF AN ACID FUJI PHOTO FILM CO., LTD. (JP) 1981-02-17 US disclosed
US-4221710-A PRESSURE SENSITIVE RECORDING SHEET FUJI PHOTO FILM CO., LTD. (JP) 1980-09-09 US disclosed