SCHEMBL5146387

SCHEMBL5146387

C=C(F)C(=O)OC12CC3CC(CC(C)(C3)C1)C2

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5667952 0.86 GRIN1 (0.37)
SCHEMBL10053101 0.86 TSHR (0.40) TSHR
SCHEMBL5144548 0.84 TSHR (0.36) TSHR
SCHEMBL14523960 0.83 PKM (0.37)
SCHEMBL22769989 0.81 CYP19A1 (0.38) TSHR
SCHEMBL5608131 0.78 TSHR (0.44) TSHR
SCHEMBL5176210 0.78 TSHR (0.44) TSHR
SCHEMBL1817331 0.78 TSHR (0.39) TSHR
SCHEMBL20697766 0.76 TSHR (0.40) TSHR
SCHEMBL12432875 0.76 TSHR (0.40) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1581595-A4 OPTICAL MEMBERS AND POLYMERIZABLE COMPOSITIONS AND THIO COMPOUNDS FOR PRODUCING THEM FUJIFILM CORP (JP) 2007-03-21 EP disclosed
US-20060178457-A1 Optical members and polymerizable compositions and thio compounds for producing them FUJIFILM CORPORATION (JP) 2006-08-10 US disclosed
EP-1581595-A1 OPTICAL MEMBERS AND POLYMERIZABLE COMPOSITIONS AND THIO COMPOUNDS FOR PRODUCING THEM FUJI PHOTO FILM CO., LTD. (JP) 2005-10-05 EP disclosed
WO-2004061009-A1 OPTICAL MEMBERS AND POLYMERIZABLE COMPOSITIONS AND THIO COMPOUNDS FOR PRODUCING THEM FUJI PHOTO FILM CO., LTD. (JP) 2004-07-22 WO disclosed