Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 4/20 | 0.66 |
| ▸ | MIF | P14174 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681082 | 0.88 | MEN1 (0.70) | SLC16A3MIFMAOBALDH1A1HPGD | |
| SCHEMBL24176806 | 0.84 | SLC16A3 (0.72) | SLC16A3MAOBALDH1A1HPGDMEN1 | |
| SCHEMBL2030497 | 0.81 | SLC16A3 (0.81) | SLC16A3MIFMAOBALDH1A1HPGD | |
| SCHEMBL839032 | 0.80 | SLC16A3 (1.00) | SLC16A3MAOBALDH1A1HPGDMEN1 | |
| SCHEMBL2031972 | 0.80 | SLC16A3 (0.78) | SLC16A3MIFMAOBALDH1A1HPGD | |
| SCHEMBL31669653 | 0.79 | SLC16A3 (0.68) | SLC16A3MAOBALDH1A1HPGDMEN1 | |
| SCHEMBL28456792 | 0.79 | SLC16A3 (0.76) | SLC16A3MIFMAOBALDH1A1HPGD | |
| SCHEMBL14111521 | 0.79 | SLC16A3 (0.76) | SLC16A3MIFMAOBALDH1A1HPGD | |
| SCHEMBL2911594 | 0.79 | MAOB (0.80) | SLC16A3MIFMAOBALDH1A1HPGD | |
| SCHEMBL11225033 | 0.76 | SLC16A3 (0.72) | SLC16A3MIFMAOBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1624900-A4 | METHODS FOR BINDING AGENTS TO BETA-AMYLOID PLAQUES | UNIV CALIFORNIA (US) | 2007-05-02 | — | — | EP | disclosed |
| US-20070053831-A1 | Methods for binding agents to b-amyloid plaques | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-03-08 | — | — | US | disclosed |
| EP-1624900-A2 | METHODS FOR BINDING AGENTS TO BETA-AMYLOID PLAQUES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-02-15 | — | — | EP | disclosed |
| WO-2005040337-A2 | METHODS FOR BINDING AGENTS TO β-AMYLOID PLAQUES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070053831-A1 | Methods for binding agents to b-amyloid plaques | APBA1, CLTB, FABP7 | SLC16A3 2974/4885MIF 2127/4885MAOB 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.