SCHEMBL5146639

SCHEMBL5146639

CCCCCCCCCCC(C(=O)O)(c1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.46
DRD3 P35462 2/20 0.46
DRD2 P14416 1/20 0.46
GAA P10253 1/20 0.45
CES2 O00748 2/20 0.45
CES1 P23141 2/20 0.45
SCN5A Q14524 3/20 0.44
SCN9A Q15858 3/20 0.44
NAAA Q02083 1/20 0.44
DRD4 P21917 1/20 0.42
KIF11 P52732 1/20 0.42
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
CYP2C19 P33261 1/20 0.42
SCN1A P35498 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7005929 1.00 OPRM1 (0.46) OPRM1DRD3DRD2GAACES2
SCHEMBL31112166 1.00 OPRM1 (0.46) OPRM1DRD3DRD2GAACES2
SCHEMBL20564993 1.00 OPRM1 (0.46) OPRM1DRD3DRD2GAACES2
SCHEMBL5147680 1.00 OPRM1 (0.46) OPRM1DRD3DRD2GAACES2
SCHEMBL3923946 1.00 OPRM1 (0.46) OPRM1DRD3DRD2GAACES2
SCHEMBL5705335 1.00 OPRM1 (0.46) OPRM1DRD3DRD2GAACES2
SCHEMBL7025068 1.00 OPRM1 (0.46) OPRM1DRD3DRD2GAACES2
SCHEMBL4775572 0.98 OPRM1 (0.47) OPRM1DRD3DRD2GAACES2
SCHEMBL27572321 0.93 OPRM1 (0.49) OPRM1DRD3DRD2CES2CES1
SCHEMBL11745181 0.87 GPR84 (0.46) CES2CES1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3625283-B1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE BV (NL) 2025-05-07 EP disclosed
US-11548980-B2 Polyester copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2023-01-10 US disclosed
US-20210139645-A1 Polyester Copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2021-05-13 US disclosed
EP-3625283-A1 POLYESTER COPOLYMER Avantium Knowledge Centre B.V. (NL) 2020-03-25 EP disclosed
CN-110914334-A Polyester copolymer 阿凡田知识中心有限公司 2020-03-24 CN disclosed
WO-2018211132-A1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2018-11-22 WO disclosed
EP-1476504-B1 THERMOPLACTIC RESIN COMPOSITION AND METHOD 0F IMPROVING APPEARANCE SABIC INNOVATIVE PLASTICS IP (NL) 2013-07-03 EP disclosed
US-7214732-B2 Thermoplastic resin composition and method of improving appearance GENERAL ELECTRIC COMPANY (US) 2007-05-08 US disclosed
EP-1476504-A1 THERMOPLACTIC RESIN COMPOSITION AND METHOD 0F IMPROVING APPEARANCE GENERAL ELECTRIC COMPANY (US) 2004-11-17 EP disclosed
US-20030162871-A1 Thermoplastic resin composition and method of improving appearance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2003-08-28 US disclosed
WO-2003066724-A1 THERMOPLACTIC RESIN COMPOSITION AND METHOD 0F IMPROVING APPEARANCE GENERAL ELECTRIC COMPANY (US) 2003-08-14 WO disclosed
US-6197917-B1 Method for manufacturing polycarbonate for optical use GENERAL ELECTRIC COMPANY 2001-03-06 US disclosed
US-5514767-A Hot-melt polycondensation method for manufacturing a polycarbonate composition GENERAL ELECTRIC COMPANY (US) 1996-05-07 US disclosed
EP-0286336-B1 CORROSION INHIBITORS EXXON CHEMICAL PATENTS INC. (US) 1991-10-09 EP disclosed
EP-0286336-A1 Corrosion inhibitors EXXON CHEMICAL PATENTS INC. (US) 1988-10-12 EP disclosed
US-4737160-A DETERGENTS PHILLIPS PETROLEUM COMPANY (US) 1988-04-12 US disclosed
US-4716252-A FLUORINE-CONTAINING ORGANIC SULFONIC ACID ACYLATION CATALYST BAYER AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed
EP-0180910-A2 Reaction products of amido-amine and epoxide useful as fuel additives PHILLIPS PETROLEUM COMPANY (US) 1986-05-14 EP disclosed
US-4504280-A Fuel additives from SO2 treated mixtures of amides and esters derived from vegetable oil, tall oil acid, or aralkyl acid PHILLIPS PETROLEUM COMPANY (US) 1985-03-12 US disclosed
EP-0016972-A1 Compound useful as detergent additive, compositions comprising a lubricating oil or hydrocarbon fuel, and method for maintaining the cleanliness of an internal combustion engine PHILLIPS PETROLEUM COMPANY (US) 1980-10-15 EP disclosed