Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6470319 | 0.82 | L3MBTL1 (0.37) | KDM4EL3MBTL1HPGDKMT2AMEN1 | |
| SCHEMBL7178170 | 0.80 | L3MBTL1 (0.37) | KDM4EL3MBTL1HPGDNPSR1MCOLN3 | |
| SCHEMBL2496206 | 0.73 | HPGD (0.39) | KDM4EL3MBTL1HPGDNPSR1MCOLN3 | |
| SCHEMBL611536 | 0.72 | KDM4E (0.35) | KDM4EL3MBTL1HPGDNPSR1MCOLN3 | |
| SCHEMBL2499311 | 0.72 | KDM4E (0.41) | KDM4EL3MBTL1HPGDNPSR1MCOLN3 | |
| SCHEMBL27976891 | 0.72 | HPGD (0.41) | KDM4EL3MBTL1HPGDNPSR1MCOLN3 | |
| SCHEMBL10019207 | 0.70 | FFAR1 (0.50) | KDM4EL3MBTL1HPGDNPSR1MCOLN3 | |
| SCHEMBL6435734 | 0.69 | SLC6A2 (0.42) | L3MBTL1HPGDNPSR1MCOLN3HTT | |
| SCHEMBL10320090 | 0.69 | NPSR1 (0.39) | KDM4EL3MBTL1HPGDNPSR1MCOLN3 | |
| SCHEMBL2499307 | 0.69 | KDM4E (0.36) | KDM4EL3MBTL1HPGDNPSR1MCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214830-B2 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-05-08 | — | — | US | disclosed |
| US-7094931-B2 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-08-22 | — | — | US | disclosed |
| EP-1135399-B2 | PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES | CIBA SC HOLDING AG (CH) | 2006-08-09 | — | — | EP | disclosed |
| US-20060128959-A1 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | IGM GROUP B.V. (NL) | 2006-06-15 | — | — | US | disclosed |
| US-20050096406-A1 | Reactive diluents and alkyd resin coating compositions | PRETOT ROGER (CH) | 2005-05-05 | — | — | US | disclosed |
| US-20040248855-A1 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | IGM GROUP B.V. (NL) | 2004-12-09 | — | — | US | disclosed |
| EP-1135399-B1 | PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES | CIBA SC HOLDING AG (CH) | 2002-08-07 | — | — | EP | disclosed |
| US-5534559-A | UNSATURATED POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128959-A1 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | AGPS, PHOSPHO1, AGPAT2 | KDM4E 2976/4885L3MBTL1 2313/4885HPGD 2329/4885 |
| US-20040248855-A1 | Process for the preparation of acylphosphines, acyl oxides and acyl sulfides | AGPS, PHOSPHO1, AGPAT2 | KDM4E 3169/4885L3MBTL1 2341/4885HPGD 2040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.