Phosphine

Phosphine

SCHEMBL5146648

C=C(C)C(=O)OCCCl.P

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.55
TSHR P16473 3/20 0.53
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 3/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112379 0.98
Ammonia Solution, Strong SCHEMBL2039467 0.95 THRB (0.55) THRBTSHRALDH1A1TDP1POLB
Ammonia Solution, Strong SCHEMBL2805637 0.95 THRB (0.55) THRBTSHRALDH1A1TDP1POLB
Methacrylic Acid SCHEMBL9769573 0.91 THRB (0.52) THRBTSHRALDH1A1TDP1POLB
Trimethylammonium SCHEMBL191319 0.91 THRB (0.52) THRBTSHRALDH1A1TDP1POLB
SCHEMBL11649198 0.90 ALDH1A1 (0.60) THRBTSHRALDH1A1TDP1POLB
N,N-Dimethylethanaminium SCHEMBL17644157 0.86 THRB (0.52) THRBTSHRALDH1A1TDP1POLB
SCHEMBL11048046 0.86 THRB (0.52) THRBTSHRALDH1A1TDP1POLB
SCHEMBL8147640 0.85 THRB (0.66) THRBTSHRALDH1A1TDP1POLB
SCHEMBL31340014 0.85 THRB (0.66) THRBTSHRALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1735393-A4 CLEAR COATING COMPOSITION AND CLEAR COATING FILM FORMATION METHOD NIPPON PAINT CO LTD (JP) 2007-09-05 EP disclosed
EP-1735393-A1 CLEAR COATING COMPOSITION AND CLEAR COATING FILM FORMATION METHOD Nippon Paint Co., Ltd. (JP) 2006-12-27 EP disclosed
WO-2005100492-A1 CLEAR COATING COMPOSITION AND CLEAR COATING FILM FORMATION METHOD NIPPON PAINT CO., LTD. (JP) 2005-10-27 WO disclosed