Butyrolactone

Butyrolactone

SCHEMBL5146838

O=C(O)OCCCCOC(=O)O.O=C1CCCO1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.52
CA9 Q16790 1/20 0.52
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
PRKCA P17252 8/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9161983 0.93 CA1 (0.53) CA1CA9ALDH1A1LMNATP53
Butyrolactone SCHEMBL2386694 0.93 CA1 (0.50) CA1CA9ALDH1A1LMNATP53
SCHEMBL14931794 0.89 CA1 (0.48) CA1CA9
Butyrolactone SCHEMBL5017200 0.86 CA1 (0.44) CA1CA9ALDH1A1LMNATP53
Butyrolactone SCHEMBL4365882 0.83 CA1 (0.41) CA1CA9ALDH1A1LMNATP53
Propiolactone SCHEMBL6363098 0.81 ALDH1A1 (0.50) CA1CA9ALDH1A1LMNATP53
Acetic Acid Pentyl Ester SCHEMBL9131107 0.79 ALDH1A1 (0.50) CA1CA9ALDH1A1TP53TSHR
Butyrolactone SCHEMBL25427151 0.78 CA1 (0.67) CA1CA9ALDH1A1LMNATP53
Butyrolactone SCHEMBL7686323 0.78 CA1 (0.67) CA1CA9ALDH1A1LMNATP53
SCHEMBL16237355 0.78 MAPT (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1765526-A4 COMPOSITIONS AND METHODS FOR DRYING PATTERNED WAFERS DURING MANUFACTURE OF INTEGRATED CIRCUITRY PRODUCTS ADVANCED TECH MATERIALS (US) 2007-11-14 EP disclosed
EP-1765526-A1 COMPOSITIONS AND METHODS FOR DRYING PATTERNED WAFERS DURING MANUFACTURE OF INTEGRATED CIRCUITRY PRODUCTS ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2007-03-28 EP disclosed
WO-2005113167-A1 COMPOSITIONS AND METHODS FOR DRYING PATTERNED WAFERS DURING MANUFACTURE OF INTEGRATED CIRCUITRY PRODUCTS ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2005-12-01 WO disclosed