Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411192 | 0.80 | OR51E2 (0.31) | — | |
| SCHEMBL6897000 | 0.79 | LMNA (0.55) | NAAAEPHX1TSHRLMNAHCAR2 | |
| SCHEMBL31112374 | 0.79 | NAAA (0.48) | NAAAEPHX1TSHRLMNAHCAR2 | |
| SCHEMBL1837444 | 0.78 | NAAA (0.67) | NAAAEPHX1TSHRLMNAHCAR2 | |
| SCHEMBL1839498 | 0.78 | NAAA (0.67) | NAAAEPHX1TSHRLMNAHCAR2 | |
| SCHEMBL1834574 | 0.78 | NAAA (0.67) | NAAAEPHX1TSHRLMNAHCAR2 | |
| SCHEMBL1839030 | 0.78 | NAAA (0.67) | NAAAEPHX1TSHRLMNAHCAR2 | |
| SCHEMBL1835519 | 0.78 | NAAA (0.67) | NAAAEPHX1TSHRLMNAHCAR2 | |
| SCHEMBL1838958 | 0.78 | NAAA (0.67) | NAAAEPHX1TSHRLMNAHCAR2 | |
| SCHEMBL119774 | 0.78 | NAAA (0.67) | NAAAEPHX1TSHRLMNAHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098366-A1 | FIBROUS SCAFFOLD FOR USE IN SOFT TISSUE ENGINEERING | MOUNT SINAI HOSPITAL (CA) | 2008-08-21 | — | — | WO | disclosed |
| WO-2002049689-A2 | POLYMERIC HEART VALVE FABRICATED FROM POLYURETHANE/POLYSILICONEURETHANE BLENDS | SULZER CARBOMEDICS INC. (US) | 2002-06-27 | — | — | WO | disclosed |