SCHEMBL5146977

SCHEMBL5146977

Cc1cc(O)nc2ncnn12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
ENPP1 P22413 2/20 0.46
KDM4E B2RXH2 5/20 0.42
MAPK1 P28482 3/20 0.42
HSD17B10 Q99714 2/20 0.42
LMNA P02545 2/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
MAPT P10636 1/20 0.42
CYP1A2 P05177 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
GAA P10253 4/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ATM Q13315 1/20 0.39
POLB P06746 1/20 0.38
RXFP1 Q9HBX9 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7103183 0.80 ALDH1A1 (0.46) ALDH1A1ENPP1KDM4EMAPK1HSD17B10
SCHEMBL259453 0.80 ALDH1A1 (1.00) ALDH1A1ENPP1KDM4EMAPK1HSD17B10
SCHEMBL10887539 0.77 ALDH1A1 (0.43) ALDH1A1ENPP1KDM4EMAPK1HSD17B10
SCHEMBL9038846 0.77 ALDH1A1 (0.67) ALDH1A1ENPP1KDM4EMAPK1HSD17B10
SCHEMBL8944374 0.77 ALDH1A1 (0.43) ALDH1A1ENPP1KDM4EMAPK1HSD17B10
SCHEMBL8944049 0.74 ACVRL1 (0.41) ALDH1A1ENPP1KDM4EMAPK1HSD17B10
SCHEMBL272835 0.73 ALDH1A1 (0.67) ALDH1A1ENPP1KDM4EMAPK1HSD17B10
SCHEMBL4255764 0.73 ALDH1A1 (0.56) ALDH1A1ENPP1KDM4EMAPK1HSD17B10
SCHEMBL5164814 0.72 ALDH1A1 (0.65) ALDH1A1ENPP1KDM4EMAPK1HSD17B10
SCHEMBL8421909 0.72 ALDH1A1 (0.65) ALDH1A1ENPP1KDM4EMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1251396-A2 Methods for making photothermographic emulsions and materials EASTMAN KODAK COMPANY (US) 2002-10-23 EP claimed
US-6413710-B1 USING ORGANONITROGEN RING COMPOUND EASTMAN KODAK COMPANY 2002-07-02 US claimed
US-4126472-A Process of making a lithographic photosensitive silver halide emulsion having reduced susceptibility to pressure containing an iridium compound, a hydroxytetrazaindene and a polyoxyethylene FUJI PHOTO FILM CO., LTD. (JP) 1978-11-21 US claimed
US-4108662-A Process for developing photographic light-sensitive materials for the graphic arts FUJI PHOTO FILM CO., LTD. (JP) 1978-08-22 US claimed
US-4078937-A SULFUR, HYDROXYTETRAAZAINDENE FUJI PHOTO FILM CO., LTD. (JA) 1978-03-14 US claimed
US-20170216295-A1 CCR9 ANTAGONIST COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2017-08-03 US disclosed
US-20070236764-A1 SILVER HALIDE HOLOGRAHIC SENSITIVE MATERIAL AND SYSTEM FOR TAKING HOLOGRAHIC IMAGES BY USING THE SAME FUJIFILM CORPORATION 2007-10-11 US disclosed
EP-1217432-B1 Silver halide photographic light-sensitive material and method for processing the same FUJIFILM CORP (JP) 2007-08-15 EP disclosed
US-7241564-B2 Silver halide holographic sensitive material and system for taking holographic images by using the same FUJIFILM CORPORATION (JP) 2007-07-10 US disclosed
EP-1798608-A1 Hologram production method and hologram production system employing silver halide photosensitive material Fujifilm Corporation (JP) 2007-06-20 EP disclosed
US-20070134559-A1 Hologram production method and hologram production system employing silver halide photosensitive material FUJIFILM CORPORATION (JP) 2007-06-14 US disclosed
EP-1691237-A2 Holographic recording material and holographic recording method FUJI PHOTO FILM CO., LTD. (JP) 2006-08-16 EP disclosed
EP-0122125-A1 Silver halide emulsion KONICA CORPORATION (JP) 1984-10-17 EP disclosed
EP-0121435-A1 Silver halide photographic materials KONICA CORPORATION (JP) 1984-10-10 EP disclosed
EP-0107488-A2 Silver halide emulsions KONICA CORPORATION (JP) 1984-05-02 EP disclosed
EP-0091788-A2 Silver halide photographic material KONICA CORPORATION (JP) 1983-10-19 EP disclosed
EP-0089101-A2 Direct positive image-forming process KONICA CORPORATION (JP) 1983-09-21 EP disclosed
US-4126472-A Process of making a lithographic photosensitive silver halide emulsion having reduced susceptibility to pressure containing an iridium compound, a hydroxytetrazaindene and a polyoxyethylene FUJI PHOTO FILM CO., LTD. (JP) 1978-11-21 US disclosed
US-4108662-A Process for developing photographic light-sensitive materials for the graphic arts FUJI PHOTO FILM CO., LTD. (JP) 1978-08-22 US disclosed
US-3977880-A Direct-positive emulsion containing silver halide grains internally doped with metal ions, surface ripened with gold and sulfur compound and fogged by light exposure FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170216295-A1 CCR9 ANTAGONIST COMPOUNDS CCR9, CCR1, CCR10 ALDH1A1 1264/4885ENPP1 1752/4885KDM4E 3628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.