Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | BCHE | P06276 | 5/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1077355 | 0.84 | DHODH (0.33) | ACHEBCHEATMRORCDHODH | |
| SCHEMBL15132715 | 0.76 | ATM (0.62) | ATMTP53LMNARAB9A | |
| SCHEMBL30753925 | 0.70 | ATM (0.44) | ATMDHODH | |
| SCHEMBL169389 | 0.70 | ATM (0.44) | ATMDHODH | |
| SCHEMBL5722087 | 0.69 | DHODH (0.34) | ATMDHODHLMNAKDM4E | |
| SCHEMBL17338118 | 0.69 | LMNA (0.51) | LMNA | |
| SCHEMBL1259950 | 0.69 | HTT (0.57) | POLBLMNAKDM4E | |
| SCHEMBL4629948 | 0.68 | MAPK1 (0.42) | ATMPOLBLMNAP2RY1KDM4E | |
| SCHEMBL4683580 | 0.67 | CHRM3 (0.49) | — | |
| SCHEMBL1836123 | 0.66 | HTT (0.46) | POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893024-A2 | ACTIVE SUBSTANCE COMBINATIONS | Bayer CropScience Aktiengesellschaft (DE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006131230-A2 | ACTIVE SUBSTANCE COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2006-12-14 | — | — | WO | disclosed |