Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722087 | 0.85 | DHODH (0.34) | DHODHATMIRAK4LMNA | |
| SCHEMBL5147003 | 0.84 | ACHE (0.36) | DHODHATMLMNABCHEACHE | |
| SCHEMBL169389 | 0.83 | ATM (0.44) | DHODHATMIRAK4 | |
| SCHEMBL30753925 | 0.83 | ATM (0.44) | DHODHATMIRAK4 | |
| SCHEMBL4975597 | 0.81 | CHRM3 (0.34) | ATMIRAK4LMNA | |
| SCHEMBL1683038 | 0.78 | TSHR (0.44) | LMNAL3MBTL1 | |
| SCHEMBL3039851 | 0.77 | CHRM3 (0.44) | — | |
| SCHEMBL5165160 | 0.77 | NPC1 (0.47) | ATMLMNABCHE | |
| SCHEMBL4648738 | 0.77 | LMNA (0.40) | LMNA | |
| SCHEMBL3041879 | 0.76 | CHRM3 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893024-A2 | ACTIVE SUBSTANCE COMBINATIONS | Bayer CropScience Aktiengesellschaft (DE) | 2008-03-05 | — | — | EP | claimed |
| WO-2006131230-A2 | ACTIVE SUBSTANCE COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2006-12-14 | — | — | WO | claimed |
| EP-2272369-A1 | Agent combinations | Bayer CropScience AG (DE) | 2011-01-12 | — | — | EP | disclosed |
| EP-2263462-A1 | Agent combinations | Bayer CropScience AG (DE) | 2010-12-22 | — | — | EP | disclosed |
| EP-2260711-A2 | Agent combinations | Bayer CropScience AG (DE) | 2010-12-15 | — | — | EP | disclosed |
| EP-2255652-A2 | Agent combinations | Bayer CropScience AG (DE) | 2010-12-01 | — | — | EP | disclosed |
| EP-2255657-A1 | Agent combinations | Bayer CropScience AG (DE) | 2010-12-01 | — | — | EP | disclosed |
| EP-2255656-A2 | Agent combinations | Bayer CropScience AG (DE) | 2010-12-01 | — | — | EP | disclosed |
| EP-2255654-A2 | Agent combinations | Bayer CropScience AG (DE) | 2010-12-01 | — | — | EP | disclosed |
| EP-1893024-A2 | ACTIVE SUBSTANCE COMBINATIONS | Bayer CropScience Aktiengesellschaft (DE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006131230-A2 | ACTIVE SUBSTANCE COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2006-12-14 | — | — | WO | disclosed |