SCHEMBL5147226

SCHEMBL5147226

CNc1ccc(-c2ccc(NC)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.64
TSHR P16473 1/20 0.56
APP P05067 11/20 0.50
ALDH1A1 P00352 3/20 0.46
RECQL P46063 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
CASP1 P29466 1/20 0.46
HIF1A Q16665 1/20 0.46
ADRA2A P08913 1/20 0.44
ADRA2B P18089 1/20 0.44
ADRA2C P18825 1/20 0.44
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL153943 0.89 TSHR (0.67) KIF11TSHRAPPALDH1A1RECQL
SCHEMBL223709 0.88 TSHR (0.68) KIF11TSHRAPPALDH1A1HSD17B10
SCHEMBL309488 0.88 KIF11 (0.54) KIF11TSHRAPPALDH1A1RECQL
SCHEMBL24062399 0.88 KIF11 (0.54) KIF11TSHRAPPALDH1A1RECQL
SCHEMBL17283460 0.88 TSHR (0.68) KIF11TSHRAPPALDH1A1HSD17B10
SCHEMBL6161280 0.86 KIF11 (0.54) KIF11TSHRAPPALDH1A1
SCHEMBL9654351 0.86 KIF11 (0.52) KIF11TSHRAPPALDH1A1RECQL
SCHEMBL6673896 0.86 APP (0.69) KIF11TSHRAPPALDH1A1RECQL
SCHEMBL22852090 0.86 KIF11 (0.52) KIF11TSHRAPPALDH1A1RECQL
SCHEMBL2543902 0.86 CYP3A4 (0.58) KIF11TSHRAPPALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112194790-B Low-thermal-expansion transparent polyimide film and preparation method thereof 中国科学院长春应用化学研究所 2022-03-29 CN claimed
EP-2859069-B1 METHOD AND APPARATUS FOR TREATING PETROLEUM EQUIPMENT FERRARA MARCELLO (IT) 2020-10-14 EP claimed
EP-3717567-A1 A THERMOPLASTIC POLYAMIDE COMPOSITION AND A MANUFACTURING METHOD AND AN APPLICATION THEREOF BASF SE (DE) 2020-10-07 EP claimed
EP-0573573-B1 MESOGENIC GLYCIDYL AMINES DOW CHEMICAL CO (US) 1999-09-29 EP claimed
EP-0573573-A1 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1993-12-15 EP claimed
WO-1992015630-A2 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO claimed
US-4616053-A Hydrophobic polyamides BAYER AKTIENGESELLSCHAFT (DE) 1986-10-07 US claimed
EP-0166321-A2 Hydrophobic polyamides BAYER AG (DE) 1986-01-02 EP claimed
US-12624265-B2 Antistatic agent, antistatic composition comprising same, antistatic resin composition comprising same, and molded article thereof ADEKA CORPORATION (JP) 2026-05-12 US disclosed
EP-3008110-B1 METHOD FOR THE CONTINUOUS MANUFACTURE OF AN ALIPHATIC OR PARTIALLY AROMATIC POLYAMIDE BASF SE (DE) 2025-10-29 EP disclosed
US-20250163281-A1 THERMOPLASTIC RESIN COMPOSITION FOR FUSED DEPOSITION MODELING, MODELED BODY, AND METHOD FOR PRODUCING SAME ADEKA CORPORATION (JP) 2025-05-22 US disclosed
EP-4321569-B1 FLAME-RETARDANT CROSSLINKED ALIPHATIC POLYKETONES FREUDENBERG CARL KG (DE) 2025-03-26 EP disclosed
EP-4484465-A1 THERMOPLASTIC RESIN COMPOSITION FOR FUSED DEPOSITION MODELING, MODELED BODY, AND METHOD FOR PRODUCING SAME ADEKA CORPORATION (JP) 2025-01-01 EP disclosed
US-20240294753-A1 Mixture of Semi-Aromatic Polyamides and Molded Articles with Improved Weld Line Strength BASF SE (DE) 2024-09-05 US disclosed
EP-0166321-A2 Hydrophobic polyamides BAYER AG (DE) 1986-01-02 EP disclosed
US-4352696-A Process and composition THE UPJOHN COMPANY (US) 1982-10-05 US disclosed
US-4257995-A STORAGE STABILITY THE UPJOHN COMPANY (US) 1981-03-24 US disclosed
US-4258129-A IMPROVE GREEN SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
EP-0012946-A1 Process for the production of winding tapes for the high voltage insulation of electric machines and apparatuses, and winding tape for making an insulating envelope for electric conductors KRAFTWERK UNION AKTIENGESELLSCHAFT (DE) 1980-07-09 EP disclosed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624265-B2 Antistatic agent, antistatic composition comprising same, antistatic resin composition comprising same, and molded article thereof SORD, SUCLA2, SUCLG1 KIF11 3695/4885TSHR 4867/4885APP 3812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.