Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 1.00 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | ITGB2 | P05107 | 6/20 | 0.73 |
| ▸ | ITGAM | P11215 | 6/20 | 0.73 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.71 |
| ▸ | CASP3 | P42574 | 2/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.70 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.57 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147227 | 1.00 | MEN1 (1.00) | MEN1KMT2APOLBL3MBTL1CTDSP1 | |
| SCHEMBL6392210 | 0.93 | MEN1 (0.87) | MEN1KMT2APOLBL3MBTL1CTDSP1 | |
| SCHEMBL6392207 | 0.93 | MEN1 (0.87) | MEN1KMT2APOLBL3MBTL1CTDSP1 | |
| SCHEMBL6390408 | 0.91 | MEN1 (0.84) | MEN1KMT2APOLBL3MBTL1CTDSP1 | |
| SCHEMBL6390413 | 0.91 | MEN1 (0.84) | MEN1KMT2APOLBL3MBTL1CTDSP1 | |
| SCHEMBL46558 | 0.84 | ITGB2 (1.00) | MEN1KMT2APOLBL3MBTL1CTDSP1 | |
| SCHEMBL5164720 | 0.84 | MEN1 (0.72) | MEN1KMT2APOLBL3MBTL1CTDSP1 | |
| SCHEMBL5164718 | 0.84 | MEN1 (0.72) | MEN1KMT2APOLBL3MBTL1CTDSP1 | |
| SCHEMBL12094536 | 0.83 | KMT2A (0.74) | MEN1KMT2APOLBL3MBTL1CTDSP1 | |
| SCHEMBL29441247 | 0.83 | KMT2A (0.74) | MEN1KMT2APOLBL3MBTL1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718308-A4 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PAINCEPTOR PHARMA CORP (CA) | 2007-07-18 | — | — | EP | disclosed |
| EP-1718308-A2 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PainCeptor Pharma Corp. (CA) | 2006-11-08 | — | — | EP | disclosed |
| US-20050282840-A1 | Methods of modulating neurotrophin-mediated activity | PAINCEPTOR PHARMA CORPORATION (CA) | 2005-12-22 | — | — | US | disclosed |
| WO-2005076695-A2 | METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY | PAINCEPTOR PHARMA CORPORATION (CA) | 2005-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282840-A1 | Methods of modulating neurotrophin-mediated activity | NGF, BDNF, NTRK2 | MEN1 4004/4885KMT2A 4410/4885POLB 2945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.