Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Dipyridyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.93 |
| ▸ | LMNA | P02545 | 3/20 | 0.93 |
| ▸ | CCR1 | P32246 | 3/20 | 0.93 |
| ▸ | CCR5 | P51681 | 3/20 | 0.93 |
| ▸ | CCR8 | P51685 | 3/20 | 0.93 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.93 |
| ▸ | POLB | P06746 | 1/20 | 0.93 |
| ▸ | METAP1 | P53582 | 1/20 | 0.93 |
| ▸ | BLM | P54132 | 1/20 | 0.93 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.93 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.93 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.93 |
| ▸ | NPC1 | O15118 | 6/20 | 0.74 |
| ▸ | TP53 | P04637 | 4/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL30076648 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL30141598 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29506433 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL30071075 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL9638434 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29668155 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL501794 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29438565 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL2349545 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29438564 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039621-A | Photo-crosslinking liquid photonic crystal hydrogel suitable for direct-writing 3D printing | 浙江理工大学 | 2024-11-29 | — | — | CN | claimed |
| CN-118048784-A | Flame-retardant functional layer on surface of fabric, preparation method of flame-retardant functional layer and flame-retardant fabric | 中国石油化工股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-116283765-A | Chlorotrifluoromethylation method of inactive olefin | 苏州大学 | 2023-06-23 | — | — | CN | claimed |
| CN-110467527-B | Method for preparing trans-D-chrysanthemic acid | 中国科学院大连化学物理研究所 | 2022-05-31 | — | — | CN | claimed |
| CN-119431464-A | Ruthenium polypyridine complex with multi-ring and quaternary ammonium salt structure, and preparation method and application thereof | 江西正梦新材料有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119119129-A | Heterogeneous bipyridine ruthenium compound and preparation method and application thereof | 昆明贵金属研究所 | 2024-12-13 | — | — | CN | disclosed |
| CN-118459510-A | Ruthenium polypyridine complex with azole skeleton structure, and preparation method and application thereof | 江西科技师范大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-118108753-A | N, N-dialkyl thioformyl-containing 2-silicon-based indole or pyrrole compound and synthesis method and application thereof | 杭州师范大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-118048784-A | Flame-retardant functional layer on surface of fabric, preparation method of flame-retardant functional layer and flame-retardant fabric | 中国石油化工股份有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-117836044-A | Defoaming agent, lubricating oil composition containing defoaming agent, and machine using lubricating oil composition | DIC株式会社 | 2024-04-05 | — | — | CN | disclosed |
| CN-111961088-B | Method for preparing cis-bis (2, 2' -bipyridine) ruthenium dichloride dihydrate | 昆明贵研新材料科技有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-116710542-A | Defoaming agent, lubricating oil composition containing defoaming agent, and machine using lubricating oil composition | DIC株式会社 | 2023-09-05 | — | — | CN | disclosed |
| WO-2004104042-A1 | A BIOELASTOMER | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-12-02 | — | — | WO | disclosed |
| WO-2004104043-A1 | A SYNTHETIC BIOELASTOMER | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-12-02 | — | — | WO | disclosed |
| WO-2001053808-A9 | PHASE-MODULATION FLUOROMETER AND METHOD FOR MEASURING NANOSECOND LIFETIMES USING A LOCK-IN AMPLIFIER | UNIV MARYLAND BIOTECH INST (US) | 2002-10-17 | — | — | WO | disclosed |
| US-6426505-B1 | Phase-modulation fluorometer and method for measuring nanosecond lifetimes using a lock-in amplifier | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE | 2002-07-30 | — | — | US | disclosed |
| CN-1087745-C | Composite photosensing agnet of eosin-dipyridine ruthonium and its synthesis process and application | CHINESE ACAD INST CHEMISTRY (CN) | 2002-07-17 | — | — | CN | disclosed |
| WO-2001053808-A1 | PHASE-MODULATION FLUOROMETER AND METHOD FOR MEASURING NANOSECOND LIFETIMES USING A LOCK-IN AMPLIFIER | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2001-07-26 | — | — | WO | disclosed |
| EP-0538681-B1 | Process for the preparation of monovinyl ethers | BASF AG (DE) | 1998-01-07 | — | — | EP | disclosed |
| EP-0538681-A1 | Process for the preparation of monovinyl ethers | BASF Aktiengesellschaft (DE) | 1993-04-28 | — | — | EP | disclosed |