Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Dipyridyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.93 |
| ▸ | LMNA | P02545 | 3/20 | 0.93 |
| ▸ | CCR1 | P32246 | 3/20 | 0.93 |
| ▸ | CCR5 | P51681 | 3/20 | 0.93 |
| ▸ | CCR8 | P51685 | 3/20 | 0.93 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.93 |
| ▸ | POLB | P06746 | 1/20 | 0.93 |
| ▸ | METAP1 | P53582 | 1/20 | 0.93 |
| ▸ | BLM | P54132 | 1/20 | 0.93 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.93 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.93 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.93 |
| ▸ | NPC1 | O15118 | 6/20 | 0.74 |
| ▸ | TP53 | P04637 | 4/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL30076648 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL30141598 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29506433 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL30071075 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL9638434 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL5147238 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29668155 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29438565 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL2349545 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29438564 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 419 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078270-A1 | THREE-DIMENSIONAL SURFACE PATTERNING | NAT RES COUNCIL CANADA (CA) | 2026-03-19 | — | — | US | claimed |
| US-20260071174-A1 | PHOTOCROSSLINKABLE BIOINK COMPOSITION FOR THREE-DIMENSIONAL PRINTING AND METHOD OF FABRICATING BIOCOMPATIBLE THREE-DIMENSIONAL HYDROGEL CONSTRUCT | UNIV CITY HONG KONG (HK) | 2026-03-12 | — | — | US | claimed |
| EP-4696341-A1 | MEDICAL DEVICE AND SYSTEM, AND PREPARATION METHOD | Shanghai MicroPort Medical (Group) Co., Ltd. (CN) | 2026-02-18 | — | — | EP | claimed |
| US-20260036897-A1 | REPAIR PROCESS FOR CLEAR DEFECTS ON EUV PSM MASKS | ZEISS CARL SMT GMBH (DE) | 2026-02-05 | — | — | US | claimed |
| WO-2024223530-A1 | REPAIR PROCESS FOR CLEAR DEFECTS ON EUV PSM MASKS | CARL ZEISS SMT GMBH (DE) | 2024-10-31 | — | — | WO | claimed |
| WO-2024201298-A1 | ELECTROCHEMICAL BIOSENSOR BASED ON A MXENE TRANSDUCER | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2024-10-03 | — | — | WO | claimed |
| EP-4429872-A1 | VAT POLYMERIZATION PROCESS | Polyfos 3D Ltd (IL) | 2024-09-18 | — | — | EP | claimed |
| US-20240182865-A1 | VISIBLE LIGHT POLYMERIZATION OF POLYETHYLENE GLYCOL (PEG) HYDROGELS | STEM PHARM, INCORPORATED | 2024-06-06 | — | — | US | claimed |
| WO-2024103022-A1 | POLYDOPAMINE ENCAPSULATED MATERIALS AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2024-05-16 | — | — | WO | claimed |
| CN-117403265-A | Porous multi-metal heterogeneous alkaline hydrogen production electrode and preparation method and application thereof | 同济大学 | 2024-01-16 | — | — | CN | claimed |
| WO-2000071028-A1 | IMPROVED METHODS AND APPARATUS FOR MULTI-PHOTON PHOTO-ACTIVATION AND DETECTION OF MOLECULAR AGENTS | PHOTOGEN, INC. (US) | 2000-11-30 | — | — | WO | claimed |
| EP-1032321-A4 | METHOD FOR IMPROVED SELECTIVITY IN PHOTO-ACTIVATION AND DETECTION OF MOLECULAR DIAGNOSTIC AGENTS | PHOTOGEN INC (US) | 2000-09-06 | — | — | EP | claimed |
| EP-1032321-A1 | METHOD FOR IMPROVED SELECTIVITY IN PHOTO-ACTIVATION AND DETECTION OF MOLECULAR DIAGNOSTIC AGENTS | Photogen, Inc. (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0977592-A1 | METHOD FOR IMPROVED SELECTIVITY IN PHOTO-ACTIVATION OF MOLECULAR AGENTS | Photogen, Inc. (US) | 2000-02-09 | — | — | EP | claimed |
| US-5998597-A | THE TREATMENT OF A PARTICULAR VOLUME OF PLANT OR ANIMAL TISSUE COMPRISING THE STEPS OF TREATING THE PLANT OR ANIMAL TISSUE WITH AT LEAST ONE PHOTO-ACTIVE MOLECULAR AGENT. | PHOTOGEN, INC. (US) | 1999-12-07 | — | — | US | claimed |
| US-5832931-A | Method for improved selectivity in photo-activation and detection of molecular diagnostic agents | PHOTOGEN, INC. (US) | 1998-11-10 | — | — | US | claimed |
| US-5829448-A | ANTITUMOR | PHOTOGEN, INC. (US) | 1998-11-03 | — | — | US | claimed |
| WO-1998018398-A1 | METHOD FOR IMPROVED SELECTIVITY IN PHOTO-ACTIVATION AND DETECTION OF MOLECULAR DIAGNOSTIC AGENTS | PHOTOGEN, INC. (US) | 1998-05-07 | — | — | WO | claimed |
| WO-1998018399-A1 | METHOD FOR IMPROVED SELECTIVITY IN PHOTO-ACTIVATION OF MOLECULAR AGENTS | PHOTOGEN, INC. (US) | 1998-05-07 | — | — | WO | claimed |
| EP-0432262-B1 | THERMOMETER | TERUMO CORP (JP) | 1995-07-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078270-A1 | THREE-DIMENSIONAL SURFACE PATTERNING | ITGB3, VCL, ITGAM | KDM4E 2344/4885LMNA 1728/4885CCR1 4085/4885 |
| US-20260036897-A1 | REPAIR PROCESS FOR CLEAR DEFECTS ON EUV PSM MASKS | PML, MUS81, PSMD14 | KDM4E 2094/4885LMNA 584/4885CCR1 3975/4885 |
| US-20260071174-A1 | PHOTOCROSSLINKABLE BIOINK COMPOSITION FOR THREE-DIMENSIONAL PRINTING AND METHOD OF FABRICATING BIOCOMPATIBLE THREE-DIMENSIONAL HYDROGEL CONSTRUCT | CRABP2, LCP2, PSTPIP2 | KDM4E 3581/4885LMNA 2524/4885CCR1 3902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.