Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182541 | 0.83 | LMNA (1.00) | LMNATDP1POLBCASP6L3MBTL1 | |
| SCHEMBL9621839 | 0.83 | LMNA (0.76) | LMNATDP1POLBCASP6L3MBTL1 | |
| SCHEMBL20107836 | 0.81 | LMNA (0.73) | LMNATDP1POLBCASP6L3MBTL1 | |
| SCHEMBL5180649 | 0.79 | LMNA (0.84) | LMNATDP1POLBCASP6L3MBTL1 | |
| SCHEMBL15886469 | 0.79 | LMNA (0.70) | LMNATDP1POLBCASP6L3MBTL1 | |
| SCHEMBL9333110 | 0.79 | LMNA (0.70) | LMNATDP1POLBCASP6L3MBTL1 | |
| SCHEMBL952927 | 0.79 | LMNA (0.70) | LMNATDP1POLBCASP6L3MBTL1 | |
| SCHEMBL3149604 | 0.78 | — | — | |
| SCHEMBL5182683 | 0.78 | LMNA (0.81) | LMNATDP1POLBCASP6L3MBTL1 | |
| SCHEMBL14336999 | 0.76 | LMNA (0.66) | LMNATDP1POLBCASP6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836164-A1 | 11C-LABELED BENZYL-LACTAM COMPOUNDS AND THEIR USE AS IMAGING AGENTS | Pfizer Products Inc. (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006075226-A1 | 11C-LABELED BENZYL-LACTAM COMPOUNDS AND THEIR USE AS IMAGING AGENTS | PFIZER PRODUCTS INC. (US) | 2006-07-20 | — | — | WO | disclosed |