Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3059284 | 0.82 | SLC2A1 (0.44) | NCF1SLC2A1KCNH2MTNR1BDDR2 | |
| SCHEMBL11948039 | 0.80 | NCF1 (0.39) | KDM4ENCF1KMT2AKCNH2MTNR1B | |
| SCHEMBL3063850 | 0.79 | NCF1 (0.41) | KDM4ENCF1LMNAMTNR1BMAPK1 | |
| SCHEMBL11947994 | 0.78 | SLC2A1 (0.47) | NCF1SLC2A1KCNH2 | |
| SCHEMBL3059462 | 0.77 | NCF1 (0.48) | KDM4ENCF1KMT2AKCNH2LMNA | |
| SCHEMBL11948021 | 0.76 | NCF1 (0.40) | KDM4ENCF1SLC2A1MTNR1BMAPK1 | |
| SCHEMBL11947997 | 0.76 | POLB (0.46) | KDM4ELMNANPSR1 | |
| SCHEMBL11948017 | 0.75 | SLC2A1 (0.38) | KDM4ENCF1SLC2A1 | |
| SCHEMBL11947996 | 0.75 | L3MBTL1 (0.45) | KDM4ENCF1SLC2A1MTNR1BMAPK1 | |
| SCHEMBL3072655 | 0.75 | NCF1 (0.37) | KDM4ENCF1KMT2AKCNH2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863483-A1 | BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS | Janssen Pharmaceutica, N.V. (BE) | 2007-12-12 | — | — | EP | claimed |
| WO-2006105289-A1 | BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-05 | — | — | WO | claimed |