Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PPID | Q08752 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | PPIB | P23284 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | PPIG | Q13427 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144720 | 0.86 | USP2 (0.50) | MEN1KMT2ASMN1; SMN2PPIDEPHX1 | |
| SCHEMBL970225 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2PPIDEPHX1PTPN1NPC1 | |
| SCHEMBL27673646 | 0.79 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2EPHX1PTPN1 | |
| SCHEMBL754248 | 0.79 | KMT2A (0.58) | KMT2ASMN1; SMN2PTPN1NPC1ALDH1A1 | |
| SCHEMBL15652114 | 0.78 | PPID (0.65) | MEN1KMT2ASMN1; SMN2PPIDEPHX1 | |
| SCHEMBL4588276 | 0.78 | MEN1 (0.81) | MEN1KMT2ASMN1; SMN2EPHX1NPC1 | |
| SCHEMBL14500628 | 0.78 | HTT (0.58) | KMT2APPIDEPHX1ALDH1A1MAPT | |
| SCHEMBL12211276 | 0.78 | HPGD (0.58) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL13317681 | 0.78 | USP2 (0.56) | MEN1KMT2ASMN1; SMN2PPIDEPHX1 | |
| SCHEMBL16430410 | 0.76 | CYP3A4 (0.61) | MEN1KMT2AALDH1A1EPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259907-A1 | ARYL AND ARYLALKYLENYL SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259907-A1 | ARYL AND ARYLALKYLENYL SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES | IL2, TSLP, IFNG | MEN1 4176/4885KMT2A 3086/4885SMN1; SMN2 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.