Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044262 | 0.95 | TLR8 (0.36) | TLR8KDM4EPOLBTDP1PDE4A | |
| SCHEMBL801378 | 0.94 | TLR8 (0.34) | TLR8KDM4EPOLBTDP1PDE4A | |
| SCHEMBL14610194 | 0.92 | TLR8 (0.38) | TLR8KDM4EPOLBTDP1PDE4A | |
| SCHEMBL13044275 | 0.88 | TLR8 (0.34) | TLR8KDM4EPOLBTDP1PDE4A | |
| SCHEMBL801119 | 0.88 | KDM4E (0.33) | TLR8KDM4EPOLBTDP1PDE4A | |
| SCHEMBL12664828 | 0.84 | TLR8 (0.35) | TLR8KDM4EPOLBTDP1PDE4A | |
| SCHEMBL13044268 | 0.83 | KDM4E (0.33) | TLR8KDM4EPOLBTDP1PDE4A | |
| SCHEMBL13607200 | 0.82 | KDM4E (0.47) | TLR8KDM4EPOLBTDP1PDE4A | |
| SCHEMBL5147675 | 0.81 | TLR8 (0.45) | TLR8KDM4EPOLBPDE4APDE4B | |
| SCHEMBL13044282 | 0.79 | DHODH (0.38) | TLR8KDM4EPOLBTDP1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8398895-B2 | Conjugated polymers and their use as organic semiconductors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-19 | — | — | US | disclosed |
| US-8398895-B2 | Conjugated polymers and their use as organic semiconductors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-19 | — | — | US | disclosed |
| US-20120068121-A1 | CONJUGATED POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20120068121-A1 | CONJUGATED POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-22 | — | — | US | disclosed |
| US-7947382-B2 | Electroluminescent polymers and the use thereof | MERCK PATENT GMBH (DE) | 2011-05-24 | — | — | US | disclosed |
| US-7947382-B2 | Electroluminescent polymers and the use thereof | MERCK PATENT GMBH (DE) | 2011-05-24 | — | — | US | disclosed |
| WO-2010136112-A1 | CONJUGATED POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | WO | disclosed |
| EP-1741149-B1 | ELECTROLUMINESCENT POLYMERS AND USE THEROF | MERCK PATENT GMBH (DE) | 2008-12-24 | — | — | EP | disclosed |
| US-20070205714-A1 | Electroluminescent Polymers and the Use Thereof | MERCK PATENT GMBH (DE) | 2007-09-06 | — | — | US | disclosed |
| US-20070205714-A1 | Electroluminescent Polymers and the Use Thereof | MERCK PATENT GMBH (DE) | 2007-09-06 | — | — | US | disclosed |