SCHEMBL5147679

SCHEMBL5147679

O=C(O)c1ccc(CCc2ccccc2)cc1NS(=O)(=O)/C=C/c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.56
ALDH1A1 P00352 2/20 0.56
GAA P10253 2/20 0.56
POLB P06746 2/20 0.56
MEN1 O00255 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
KDM4E B2RXH2 1/20 0.56
HSD17B10 Q99714 1/20 0.56
ACLY P53396 3/20 0.49
PTGES2 Q9H7Z7 1/20 0.46
HTT P42858 2/20 0.45
MCL1 Q07820 1/20 0.43
PKM P14618 1/20 0.42
METAP2 P50579 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2271008 1.00 KMT2A (0.56) KMT2AALDH1A1GAAPOLBMEN1
SCHEMBL27716659 0.83 KMT2A (0.62) KMT2AALDH1A1GAAPOLBMEN1
SCHEMBL2275485 0.81 ACLY (0.61) KMT2AALDH1A1GAAPOLBMEN1
SCHEMBL2275487 0.81 ACLY (0.61) KMT2AALDH1A1GAAPOLBMEN1
SCHEMBL13561005 0.80 KMT2A (0.60) KMT2AALDH1A1GAAPOLBMEN1
SCHEMBL3559358 0.79 KMT2A (0.67) KMT2AALDH1A1GAAPOLBMEN1
SCHEMBL3552428 0.79 KMT2A (0.67) KMT2AALDH1A1GAAPOLBMEN1
SCHEMBL3559362 0.79 KMT2A (0.67) KMT2AALDH1A1GAAPOLBMEN1
SCHEMBL3552430 0.79 KMT2A (0.67) KMT2AALDH1A1GAAPOLBMEN1
SCHEMBL2276451 0.78 ACLY (0.71) ALDH1A1KDM4EHSD17B10ACLYMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed