SCHEMBL2276451

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7686172	0.83	ACLY (0.71)	ACLYMCL1KDM4EALDH1A1HPGD
	SCHEMBL2275253	0.83	ACLY (1.00)	ACLYMCL1
	SCHEMBL2275449	0.83	METAP2 (0.64)	ACLYMCL1BCL2A1KDM4EALDH1A1
	SCHEMBL2270968	0.83	ACLY (0.51)	ACLYKDM4EALDH1A1HPGDHSD17B10
	SCHEMBL6137932	0.82	ACLY (0.69)	ACLYKDM4EALDH1A1HPGDHSD17B10
	SCHEMBL2273163	0.80	ACLY (0.67)	ACLYMCL1ALDH1A1
	SCHEMBL27716715	0.80	ACLY (0.67)	ACLYMCL1KDM4EALDH1A1HSD17B10
	SCHEMBL2271008	0.78	KMT2A (0.56)	ACLYMCL1KDM4EALDH1A1HSD17B10
	SCHEMBL5147679	0.78	KMT2A (0.56)	ACLYMCL1KDM4EALDH1A1HSD17B10
	SCHEMBL4217232	0.77	KDM6B (0.61)	ACLYMCL1BCL2A1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.