Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 4/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147798 | 1.00 | KDM4E (0.52) | KDM4EPKMSTSGPR119PTPN2 | |
| SCHEMBL3380017 | 0.82 | KDM4E (0.57) | KDM4EPKMSTSGPR119PTPN2 | |
| SCHEMBL3380015 | 0.82 | KDM4E (0.57) | KDM4EPKMSTSGPR119PTPN2 | |
| SCHEMBL16395219 | 0.79 | KDM4E (0.59) | KDM4EPKMSTSGPR119PTPN2 | |
| SCHEMBL25260321 | 0.77 | MMP13 (0.55) | KDM4EPKMSTSGPR119KMT2A | |
| SCHEMBL22773318 | 0.77 | MMP13 (0.55) | KDM4EPKMSTSGPR119KMT2A | |
| SCHEMBL22773317 | 0.77 | MMP13 (0.55) | KDM4EPKMSTSGPR119KMT2A | |
| SCHEMBL441012 | 0.76 | KDM4E (0.62) | KDM4EPKMSTSGPR119PTPN2 | |
| SCHEMBL14514078 | 0.76 | KDM4E (0.53) | KDM4EPKMSTSGPR119PTPN2 | |
| SCHEMBL20202546 | 0.75 | RAB9A (0.48) | KDM4EPKMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276017-A1 | Thiadiazoline Derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276017-A1 | Thiadiazoline Derivative | BRD7, NR3C2, NR5A2 | KDM4E 3163/4885PKM 4005/4885STS 1172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.