Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5149164 | 0.97 | NPSR1 (0.56) | NPSR1L3MBTL1ALDH1A1MEN1KMT2A | |
| Fluoride Ion SCHEMBL5148074 | 0.97 | NPSR1 (0.56) | NPSR1L3MBTL1ALDH1A1MEN1KMT2A | |
| Bromide SCHEMBL5148116 | 0.89 | L3MBTL1 (0.60) | NPSR1L3MBTL1ALDH1A1MEN1KMT2A | |
| Bromide SCHEMBL5146792 | 0.87 | NPSR1 (0.71) | NPSR1L3MBTL1ALDH1A1MEN1KMT2A | |
| Bromide SCHEMBL5148045 | 0.87 | NPSR1 (0.71) | NPSR1L3MBTL1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5150273 | 0.86 | NPSR1 (0.60) | NPSR1L3MBTL1ALDH1A1MEN1KMT2A | |
| Fluoride Ion SCHEMBL5146795 | 0.86 | L3MBTL1 (0.60) | NPSR1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL125500 | 0.85 | NPSR1 (0.73) | NPSR1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL30057272 | 0.85 | NPSR1 (0.73) | NPSR1L3MBTL1ALDH1A1MEN1KMT2A | |
| Bromide SCHEMBL5148011 | 0.85 | NPSR1 (0.56) | NPSR1L3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1870495-A1 | Aqueous alkaline, cyanide-free, bath for the galvanic deposition of Zinc and Zinc alloy layers | ATOTECH DEUTSCHLAND GMBH (DE) | 2007-12-26 | — | — | EP | disclosed |