SCHEMBL5148071

SCHEMBL5148071

BrCc1cc(OC2CCCCO2)cc(OC2CCCCO2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.44
KDM4C Q9H3R0 1/20 0.36
HSD11B1 P28845 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
PTPN1 P18031 2/20 0.33
TNK2 Q07912 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PDE4B Q07343 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2464134 0.85 DHFR (0.57) DHFRKDM4CHSD11B1MEN1KMT2A
SCHEMBL883393 0.84 DHFR (0.41) DHFRKDM4CHSD11B1MEN1KMT2A
SCHEMBL5145220 0.84 DHFR (0.44) DHFRKDM4CHSD11B1MEN1KMT2A
SCHEMBL13577642 0.81 DHFR (0.38) DHFRKDM4CHSD11B1MEN1KMT2A
SCHEMBL13141127 0.81 DHFR (0.47) DHFRKDM4CHSD11B1MEN1KMT2A
SCHEMBL565682 0.81 DHFR (0.40) DHFRKDM4CHSD11B1MEN1KMT2A
SCHEMBL28926462 0.78 KDM4C (0.39) DHFRKDM4CHSD11B1MEN1KMT2A
SCHEMBL27329498 0.78 FUT7 (0.43) DHFR
SCHEMBL3184997 0.76 DHFR (0.53) DHFRKDM4CHSD11B1MEN1KMT2A
SCHEMBL566138 0.76 DHFR (0.36) DHFRKDM4CHSD11B1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7259217-B2 Controlled-architecture polymers and use thereof as separation media SYMYX TECHNOLOGIES, INC. (US) 2007-08-21 US disclosed
US-7259217-B2 Controlled-architecture polymers and use thereof as separation media SYMYX TECHNOLOGIES, INC. (US) 2007-08-21 US disclosed
US-7259217-B2 Controlled-architecture polymers and use thereof as separation media SYMYX TECHNOLOGIES, INC. (US) 2007-08-21 US disclosed
US-20060128917-A1 Controlled-architecture polymers and use thereof as separation media SYMYX TECHNOLOGIES, INC. 2006-06-15 US disclosed
US-6716948-B1 POLYFUNCTIONAL NITROXIDE INITIATORS; MULTIPLE FREE RADICAL ACRYLAMIDE LIVING POLYMERIZATION; STAR POLYMERS; REPLACEABLE CAPILLARY ELECTROPHORESIS SEPARATION MEDIA FOR BIOLOGICAL MOLECULES SUCH AS DNA SYMYX TECHNOLOGIES, INC. 2004-04-06 US disclosed
WO-2001009204-A9 CONTROLLED-ARCHITECTURE POLYMERS AND USE THEREOF AS SEPARATION MEDIA SYMYX TECHNOLOGIES INC (US) 2002-09-26 WO disclosed
WO-2001009204-A2 CONTROLLED-ARCHITECTURE POLYMERS AND USE THEREOF AS SEPARATION MEDIA SYMYX TECHNOLOGIES, INC. (US) 2001-02-08 WO disclosed