Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18868393 | 0.90 | DHFR (0.40) | DHFRMEN1KMT2AKDM4CHSD11B1 | |
| SCHEMBL7317886 | 0.90 | DHFR (0.40) | DHFRMEN1KMT2AKDM4CHSD11B1 | |
| SCHEMBL15584179 | 0.87 | DHFR (0.36) | DHFRMEN1KMT2AKDM4CHSD11B1 | |
| SCHEMBL13140896 | 0.85 | DHFR (0.57) | DHFRMEN1KMT2AKDM4CHSD11B1 | |
| SCHEMBL29646513 | 0.85 | DHFR (0.57) | DHFRMEN1KMT2AKDM4CHSD11B1 | |
| SCHEMBL862862 | 0.84 | MEN1 (0.43) | DHFRMEN1KMT2AKDM4CHSD11B1 | |
| SCHEMBL5148071 | 0.84 | DHFR (0.44) | DHFRMEN1KMT2AKDM4CHSD11B1 | |
| SCHEMBL25223911 | 0.84 | DHFR (0.45) | DHFRMEN1KMT2AKDM4CHSD11B1 | |
| SCHEMBL31052157 | 0.84 | DHFR (0.45) | DHFRMEN1KMT2AKDM4CHSD11B1 | |
| SCHEMBL13141127 | 0.81 | DHFR (0.47) | DHFRMEN1KMT2AKDM4CHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10399071-B2 | Polymer containing carboxyl group, preparation method and application thereof, supported catalyst and preparation methods thereof and preparation methods of penem antibiotic intermediate | ASYMCHEM LABORATORIES (FUXIN) CO., LTD. (CN) | 2019-09-03 | — | — | US | disclosed |
| US-7259217-B2 | Controlled-architecture polymers and use thereof as separation media | SYMYX TECHNOLOGIES, INC. (US) | 2007-08-21 | — | — | US | disclosed |
| US-7259217-B2 | Controlled-architecture polymers and use thereof as separation media | SYMYX TECHNOLOGIES, INC. (US) | 2007-08-21 | — | — | US | disclosed |
| US-7259217-B2 | Controlled-architecture polymers and use thereof as separation media | SYMYX TECHNOLOGIES, INC. (US) | 2007-08-21 | — | — | US | disclosed |
| US-20060128917-A1 | Controlled-architecture polymers and use thereof as separation media | SYMYX TECHNOLOGIES, INC. | 2006-06-15 | — | — | US | disclosed |
| US-6716948-B1 | POLYFUNCTIONAL NITROXIDE INITIATORS; MULTIPLE FREE RADICAL ACRYLAMIDE LIVING POLYMERIZATION; STAR POLYMERS; REPLACEABLE CAPILLARY ELECTROPHORESIS SEPARATION MEDIA FOR BIOLOGICAL MOLECULES SUCH AS DNA | SYMYX TECHNOLOGIES, INC. | 2004-04-06 | — | — | US | disclosed |
| WO-2001009204-A9 | CONTROLLED-ARCHITECTURE POLYMERS AND USE THEREOF AS SEPARATION MEDIA | SYMYX TECHNOLOGIES INC (US) | 2002-09-26 | — | — | WO | disclosed |
| WO-2001009204-A2 | CONTROLLED-ARCHITECTURE POLYMERS AND USE THEREOF AS SEPARATION MEDIA | SYMYX TECHNOLOGIES, INC. (US) | 2001-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10399071-B2 | Polymer containing carboxyl group, preparation method and application thereof, supported catalyst and preparation methods thereof and preparation methods of penem antibiotic intermediate | PGM2, MGAM, MRPL21 | DHFR 1737/4885MEN1 3389/4885KMT2A 1359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.