Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146769 | 0.76 | CHRM5 (0.43) | CHRM5CHRM3ALDH1A1LMNANPSR1 | |
| SCHEMBL3923220 | 0.76 | SMN1; SMN2 (0.51) | CHRM5CHRM3ALDH1A1LMNACHRM1 | |
| Trifluoroacetic Acid SCHEMBL3665235 | 0.73 | SMN1; SMN2 (0.52) | CHRM5CHRM3ALDH1A1LMNANPSR1 | |
| SCHEMBL3915618 | 0.72 | SMN1; SMN2 (0.56) | CHRM5CHRM3ALDH1A1LMNANPSR1 | |
| SCHEMBL17140945 | 0.71 | CTSK (0.38) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL17140956 | 0.71 | GAA (0.49) | ALDH1A1LMNASMN1; SMN2POLBKMT2A | |
| SCHEMBL3567330 | 0.68 | KMT2A (0.72) | ALDH1A1POLBKMT2A | |
| SCHEMBL31697584 | 0.67 | SMN1; SMN2 (0.56) | CHRM5CHRM3ALDH1A1LMNANPSR1 | |
| SCHEMBL4583404 | 0.66 | SMN1; SMN2 (0.75) | ALDH1A1LMNASMN1; SMN2TAAR1FPR2 | |
| SCHEMBL2746054 | 0.66 | SMN1; SMN2 (0.65) | ALDH1A1LMNASMN1; SMN2TAAR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299072-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299072-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | KCNA5, KCNH1, KCNK5 | CHRM5 618/4885CHRM3 1123/4885ALDH1A1 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.