SCHEMBL5149191

SCHEMBL5149191

C=Cc1coc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 11/20 0.53
MAOA P21397 6/20 0.53
PTPN1 P18031 1/20 0.53
ALDH1A1 P00352 4/20 0.46
MAPT P10636 4/20 0.46
KDM4E B2RXH2 2/20 0.46
PTGS2 P35354 1/20 0.44
PIM1 P11309 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
GLA P06280 1/20 0.41
GAA P10253 2/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1102245 0.84 MAOB (0.71) MAOBMAOAPTPN1ALDH1A1MAPT
SCHEMBL9110245 0.79 MAOB (0.50) MAOBMAOAPTPN1ALDH1A1MAPT
SCHEMBL30842883 0.78 PTPN1 (0.75) MAOBMAOAPTPN1ALDH1A1MAPT
SCHEMBL96940 0.78 PTPN1 (0.75) MAOBMAOAPTPN1ALDH1A1MAPT
SCHEMBL8051158 0.78 MAOB (0.53) MAOBMAOAPTPN1ALDH1A1MAPT
SCHEMBL12903098 0.75 MAOB (0.50) MAOBMAOAPTPN1ALDH1A1MAPT
SCHEMBL19275439 0.75 MAOB (0.50) MAOBMAOAPTPN1ALDH1A1MAPT
SCHEMBL9113323 0.75 MAOB (0.46) MAOBMAOAPTPN1ALDH1A1MAPT
SCHEMBL5689431 0.74 MAOB (0.75) MAOBMAOAPTPN1ALDH1A1MAPT
SCHEMBL20509363 0.74 ALDH1A1 (0.55) MAOBMAOAPTPN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621115-B Method for synthesizing oxime compounds under photocatalysis condition 河南大学 2023-05-23 CN disclosed
CN-114621115-A Method for synthesizing oxime compound under photocatalysis condition 河南大学 2022-06-14 CN disclosed
WO-2015014791-A1 BENZIMIDAZOLO[2,1-B][1,3]BENZOTHIAZOLES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2015-02-05 WO disclosed
US-20100247938-A1 MATERIAL FOR THREE-DIMENSIONAL MODELING, PROCESS FOR PRODUCING THREE-DIMENSIONAL MODEL, AND THREE-DIMENSIONAL MODEL FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
US-20100247938-A1 MATERIAL FOR THREE-DIMENSIONAL MODELING, PROCESS FOR PRODUCING THREE-DIMENSIONAL MODEL, AND THREE-DIMENSIONAL MODEL FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
US-20070152569-A1 Novel benzo[b]furan derivatives and their use WELL-BEING BIOCHEMICAL CORP. 2007-07-05 US disclosed
US-6300340-B1 USEFUL FOR THERAPY OF CANCER AND SOLID TUMORS ADIR ET COMPAGNIE (FR) 2001-10-09 US disclosed
US-6162822-A Bisimide compounds ADIR ET COMPAGNIE (FR) 2000-12-19 US disclosed
EP-0820985-B1 Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 2000-08-30 EP disclosed
US-5854273-A Bisimide compounds ADIR ET COMPAGNIE (FR) 1998-12-29 US disclosed
EP-0820985-A1 Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1998-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070152569-A1 Novel benzo[b]furan derivatives and their use JUND, FOSB, BRD9 MAOB 10/4885MAOA 305/4885PTPN1 4766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.