Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 17/20 | 0.34 |
| ▸ | MAOA | P21397 | 16/20 | 0.34 |
| ▸ | KDM1A | O60341 | 14/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734440 | 0.82 | KDM1A (0.38) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL3789285 | 0.81 | DDB1 (0.37) | MAOBMAOA | |
| SCHEMBL1153469 | 0.78 | KDM1A (0.44) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL20017698 | 0.77 | HTR2A (0.35) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL9100196 | 0.77 | KDM1A (0.34) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL2870312 | 0.76 | MAOA (0.39) | HTR2AHTR2CHTR2BMAOBMAOA | |
| SCHEMBL20839329 | 0.73 | MAOA (0.32) | MAOBMAOAKDM1A | |
| SCHEMBL16599817 | 0.73 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL31716197 | 0.73 | CUL4A (0.35) | MAOBMAOAKDM1A | |
| SCHEMBL5458200 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856024-A1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006092429-A1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF AKTIENGESELLSCAHFT (DE) | 2006-09-08 | — | — | WO | disclosed |
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |