Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31061408 | 1.00 | NPSR1 (0.70) | NPSR1MAPTMAPK1L3MBTL1KDM4E | |
| SCHEMBL5972208 | 0.86 | KDM4E (0.75) | MAPTKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL31606732 | 0.86 | KDM4E (0.75) | MAPTKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL13995502 | 0.86 | ATM (0.61) | NPSR1MAPTMAPK1L3MBTL1KDM4E | |
| SCHEMBL1599701 | 0.82 | KDM4E (0.69) | NPSR1MAPTKDM4EPOLBKMT2A | |
| SCHEMBL29484286 | 0.82 | KDM4E (0.69) | NPSR1MAPTKDM4EPOLBKMT2A | |
| SCHEMBL1966851 | 0.81 | KDM4E (0.69) | MAPTKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL11020362 | 0.80 | POLB (0.67) | MAPTKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL10437146 | 0.80 | KDM4E (0.71) | KDM4EPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL6991909 | 0.80 | KDM4E (0.82) | KDM4EPOLBKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598110-B1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | UNILEVER PLC (GB) | 2015-09-02 | — | — | EP | disclosed |
| EP-2598110-A2 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | Unilever PLC (GB) | 2013-06-05 | — | — | EP | disclosed |
| US-8293218-B2 | Skin care compositions comprising substituted monoamines | CONOPCO, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-8293218-B2 | Skin care compositions comprising substituted monoamines | CONOPCO, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-8293218-B2 | Skin care compositions comprising substituted monoamines | CONOPCO, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-20120027699-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120027699-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120027699-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
| WO-2012013418-A2 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | UNILEVER PLC (GB) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027699-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | TYR, CUTA, MAOA | NPSR1 2974/4885MAPT 382/4885MAPK1 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.