Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | USP14 | P54578 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5185511 | 0.84 | HRH3 (0.44) | HRH3NOTUMCHRM1HRH2HRH1 | |
| SCHEMBL5149971 | 0.77 | NOTUM (0.62) | NOTUMARJAK2ALDH1A1LMNA | |
| SCHEMBL23176209 | 0.76 | NOTUM (0.45) | NOTUMARJAK2ALDH1A1LMNA | |
| SCHEMBL5184017 | 0.76 | NOTUM (0.45) | NOTUMARJAK2ALDH1A1LMNA | |
| SCHEMBL151230 | 0.72 | HRH3 (0.70) | HRH3ALDH1A1SMN1; SMN2CCR2 | |
| SCHEMBL154169 | 0.72 | HRH3 (0.70) | HRH3ALDH1A1SMN1; SMN2CCR2 | |
| SCHEMBL150808 | 0.70 | HRH3 (0.68) | HRH3ALDH1A1SMN1; SMN2CCR2 | |
| SCHEMBL31010286 | 0.68 | HRH3 (0.42) | HRH3ALDH1A1MAPT | |
| SCHEMBL2584832 | 0.67 | ALDH1A1 (0.43) | NOTUMJAK2ALDH1A1LMNAMAPT | |
| SCHEMBL15935401 | 0.67 | HTT (0.51) | NOTUMARALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |