Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23176209 | 0.85 | NOTUM (0.45) | NOTUMJAK2MAPTALDH1A1LMNA | |
| SCHEMBL5184017 | 0.85 | NOTUM (0.45) | NOTUMJAK2MAPTALDH1A1LMNA | |
| SCHEMBL15352616 | 0.79 | ALDH1A1 (0.47) | NOTUMMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5149586 | 0.77 | HRH3 (0.43) | NOTUMJAK2MAPTALDH1A1LMNA | |
| SCHEMBL23451495 | 0.77 | NOTUM (1.00) | NOTUMMAPTCA2CA9CA1 | |
| SCHEMBL16322113 | 0.77 | NOTUM (0.59) | NOTUMMAPTALDH1A1LMNAAR | |
| SCHEMBL12438819 | 0.77 | NOTUM (0.59) | NOTUMMAPTALDH1A1SMN1; SMN2AR | |
| SCHEMBL5185511 | 0.76 | HRH3 (0.44) | NOTUMJAK2LMNAAROPRM1 | |
| SCHEMBL15603518 | 0.76 | L3MBTL1 (0.56) | NOTUMMAPTALDH1A1KDM4EELOVL1 | |
| SCHEMBL29229644 | 0.75 | AR (0.60) | NOTUMAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |