Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MYOC | Q99972 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151633 | 0.84 | MAPT (0.58) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL5151640 | 0.84 | MAPT (0.58) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL4690573 | 0.80 | MEN1 (0.79) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL17997748 | 0.80 | ALDH1A1 (0.50) | MEN1KMT2AMAPTMAPK1NPSR1 | |
| SCHEMBL12273311 | 0.79 | SMN1; SMN2 (0.42) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL5149570 | 0.79 | ALDH1A1 (0.53) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL4743116 | 0.79 | MEN1 (0.55) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL31557883 | 0.78 | MEN1 (0.60) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL4688634 | 0.77 | MEN1 (0.56) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL4688637 | 0.77 | MEN1 (0.56) | MEN1KMT2AMAPTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |