Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | NPC1 | O15118 | 3/20 | 0.79 |
| ▸ | RAB9A | P51151 | 3/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.79 |
| ▸ | MYOC | Q99972 | 1/20 | 0.79 |
| ▸ | F13A1 | P00488 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | FNTA | P49354 | 1/20 | 0.57 |
| ▸ | FNTB | P49356 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL152811 | 0.89 | KMT2A (0.74) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11390157 | 0.89 | LMNA (0.64) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11004478 | 0.88 | MEN1 (1.00) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11027238 | 0.86 | MEN1 (0.88) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11832409 | 0.86 | MEN1 (0.88) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11831801 | 0.85 | MEN1 (0.77) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL9367406 | 0.85 | KMT2A (0.77) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL5169615 | 0.85 | FFAR1 (0.69) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL5169625 | 0.85 | FFAR1 (0.69) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL17289271 | 0.84 | KMT2A (0.67) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10617706-B2 | Compounds for cancer chemotherapeutic sensitization | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2020-04-14 | — | — | US | disclosed |
| US-20190240244-A1 | COMPOUNDS FOR CANCER CHEMOTHERAPEUTIC SENSITIZATION | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2019-08-08 | — | — | US | disclosed |
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10617706-B2 | Compounds for cancer chemotherapeutic sensitization | ABCC1, MCL1, ABCC3 | MEN1 1096/4885KMT2A 1269/4885MAPT 4452/4885 |
| US-20190240244-A1 | COMPOUNDS FOR CANCER CHEMOTHERAPEUTIC SENSITIZATION | ABCC1, MCL1, ABCC3 | MEN1 1096/4885KMT2A 1269/4885MAPT 4452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.