SCHEMBL74549

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL74952	0.80	MAPT (0.47)	MAPTPOLBCYP3A4CYP2D6CYP2C9
	SCHEMBL10040365	0.79	MAPT (0.38)	MAPTPOLBRIPK1ALDH1A1TDP1
	SCHEMBL6849252	0.75	THRB (0.41)	THRBCYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL16943707	0.73	THRB (0.35)	THRBPOLBCYP3A4ALDH1A1THRA
	SCHEMBL31742092	0.73	MAPT (0.44)	MAPTCYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL5149643	0.72	MAPT (0.40)	MAPTCYP3A4CYP2D6CYP2C9CYP2C19
	SCHEMBL75375	0.71	SRC (0.41)	MAPTPOLBALDH1A1L3MBTL1TDP1
	SCHEMBL85794	0.71	MAPT (0.40)	MAPTPOLBALDH1A1L3MBTL1TDP1
	SCHEMBL10040353	0.70	SRC (0.40)	MAPTPOLBALDH1A1L3MBTL1TDP1
	SCHEMBL9554641	0.69	POLB (0.41)	MAPTPOLBALDH1A1CACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.