Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PNLIP | P16233 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4237333 | 0.91 | PKM (0.50) | PKMTAS1R3TAS1R1PTPN1PNLIP | |
| SCHEMBL5148190 | 0.90 | PKM (0.48) | PKMTAS1R3TAS1R1PPARGPTPN1 | |
| SCHEMBL5149411 | 0.88 | PKM (0.52) | PKMTAS1R3TAS1R1PNLIPCYP2C9 | |
| SCHEMBL5173994 | 0.85 | PKM (0.49) | PKMTAS1R3TAS1R1PNLIPCYP2C9 | |
| SCHEMBL4238927 | 0.84 | PKM (0.54) | PKMTAS1R3TAS1R1PNLIPMTNR1B | |
| SCHEMBL4228260 | 0.84 | PKM (0.54) | PKMTAS1R3TAS1R1CYP2C9CYP2C19 | |
| SCHEMBL5149841 | 0.83 | EPHX1 (0.50) | PTPN1PNLIPHDAC1ALDH1A1 | |
| SCHEMBL4228811 | 0.83 | PKM (0.60) | PKMTAS1R3TAS1R1MTNR1BLMNA | |
| SCHEMBL4240850 | 0.83 | PKM (0.53) | PKMTAS1R3TAS1R1PNLIP | |
| SCHEMBL4236991 | 0.83 | PKM (0.53) | PKMTAS1R3TAS1R1PNLIPCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |